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Soft tissue tumors (STTs) are a heterogeneous group of mesenchymal neoplasms requiring accurate differentiation for optimal patient management. While histopathology remains the gold standard, imaging plays a crucial role in non-invasive assessment. Multiparametric ultrasound (mpUS) has emerged as a promising, cost-effective alternative to MRI, integrating B-mode, color and power Doppler, shear wave elastography (SWE), and contrast-enhanced ultrasound (CEUS) to provide comprehensive morphological, vascular, and biomechanical insights. Each modality offers distinct yet complementary diagnostic value, enhancing accuracy and potentially reducing unnecessary biopsies. This narrative review aims to serve as a practical guide, providing a readily accessible reference for mpUS parameters useful in the differential diagnosis of soft tissue tumors.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12292126 | PMC |
http://dx.doi.org/10.3390/biomedicines13071786 | DOI Listing |
J Biomech Eng
September 2025
Texas Tech University Box 41021 Lubbock, TX 79409.
Wrist biomechanics remain incompletely understood due to the complexity of experimental measurements in this multi-bone joint system. Finite element analysis provides a powerful alternative for investigating internal variables such as carpal kinematics and displacement patterns. This technical brief compares two bone representation approaches, all-cortical versus cortical-trabecular, using two distinct finite element models developed from the same wrist CT dataset.
View Article and Find Full Text PDFBiol Cybern
September 2025
Department of Mechanical Science and Engineering, University of Illinois Urbana-Champaign, 61801, IL, USA.
In this article, a biophysically realistic model of a soft octopus arm with internal musculature is presented. The modeling is motivated by experimental observations of sensorimotor control where an arm localizes and reaches a target. Major contributions of this article are: (i) development of models to capture the mechanical properties of arm musculature, the electrical properties of the arm peripheral nervous system (PNS), and the coupling of PNS with muscular contractions; (ii) modeling the arm sensory system, including chemosensing and proprioception; and (iii) algorithms for sensorimotor control, which include a novel feedback neural motor control law for mimicking target-oriented arm reaching motions, and a novel consensus algorithm for solving sensing problems such as locating a food source from local chemical sensory information (exogenous) and arm deformation information (endogenous).
View Article and Find Full Text PDFUnfallchirurgie (Heidelb)
September 2025
Klinik für Unfall‑, Hand- und Wiederherstellungschirurgie, Universitätsklinikum Münster, Albert-Schweitzer-Campus 1, Gebäude W1, 48149, Münster, Deutschland.
The bony consolidation of fractures depends on various factors. Under optimal conditions fracture healing takes place within a few weeks. An essential requirement for fracture healing is the restoration of adequate biomechanical stability with an interfragmentary movement which is as ideal as possible.
View Article and Find Full Text PDFJ Am Acad Orthop Surg Glob Res Rev
September 2025
From the American Hip Institute Research Foundation (Dr. Quesada-Jimenez, Dr. Kahana-Rojkind, and Dr. Domb), and the American Hip Institute, Chicago, IL (Dr. Domb).
Hip pain after a total hip arthroplasty is a prevalent condition. Once aseptic loosening and infection have been ruled out, the possible entities are vast. Accurate diagnosis in this patient population is challenging because they might present in different stages of their recovery process and the potential overlap of some conditions.
View Article and Find Full Text PDFJ Surg Oncol
September 2025
Orthopedic Oncology Service, Department of Orthopedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Background: Hemicondylar fresh frozen allografts address partial knee defects while preserving native anatomy and bone stock. This study evaluated long-term survival, failure modes, and functional outcomes following hemicondylar reconstruction.
Methods: We conducted a retrospective analysis of hemicondylar fresh frozen allograft reconstructions.