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This study describes the development of the Asthma Symptom Score (ASS) and evaluates its accuracy and internal consistency in Greenlandic and Danish, using clinical interviews based on Global Initiative for Asthma guidelines as the gold standard. A cross-sectional study was conducted across all regions of Greenland, targeting citizens aged 12+, using data from the electronic medical record. The ASS ( = 94) was validated against clinical interviews using a receiver operating characteristic curve, yielding an area under the curve estimate of 0.91, indicating strong agreement. The ASS demonstrated a sensitivity of 83%, a specificity of 93%, and an overall agreement of 87%. Patients scoring 0-5 points were categorised as having controlled asthma, while those scoring 6-20 points were categorised as non-controlled. Among participants completing both the ASS and the clinical interview, 57% were classified as having non-controlled asthma. The ASS demonstrated acceptable internal consistency in both Greenlandic and Danish. These findings underscore the need for improved management of asthma in Greenland. The strong correlation between the ASS and clinical interviews suggests that the ASS may be a valuable tool in clinical practice for assessing asthma control among patients with a confirmed diagnosis. However, further validation including a larger study group, and test - retest reliability is recommended.
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http://dx.doi.org/10.1080/22423982.2025.2540684 | DOI Listing |
BMC Nurs
September 2025
Institute of Business Administration and Business Informatics, IT for the Caring Society, University of Hildesheim, Hildesheim, Germany.
Background: As populations age, informal caregivers play an increasingly vital role in long-term care, with 80% of care provided by family members in Europe. However, many individuals do not immediately recognize themselves as caregivers, especially in the early stages. This lack of awareness can increase physical and emotional stress and delay access to support services.
View Article and Find Full Text PDFAnn Surg Oncol
September 2025
Department of Surgery, Division of Surgical Oncology, UCLA David Geffen School of Medicine, Los Angeles, CA, USA.
BMJ Open
September 2025
Pandemic Sciences Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Introduction: Nipah virus (NiV) is a bat-transmitted paramyxovirus causing recurrent, high-mortality outbreaks in South and South-East Asia. As a WHO priority pathogen, efforts are underway to develop therapies like monoclonal antibodies and small-molecule antivirals, which require evaluation in clinical trials. However, trial design is challenging due to limited understanding of NiV's clinical characteristics.
View Article and Find Full Text PDFBone Jt Open
September 2025
Kadoorie, Oxford Trauma and Emergency Care, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Oxford University, Oxford, UK.
Aims: We sought to explore staff experience of a paediatric randomized controlled trial (RCT), comparing operative fixation and nonoperative treatment for displaced medial epicondyle fractures.
Methods: A total of 20 staff (eight surgeons and 12 research delivery staff) recruiting to the RCT in 18 NHS Trusts across the UK took part in a telephone/online qualitative interview. Interviews were informed by Heideggerian Phenomenology and thematic analysis.
Eur J Vasc Endovasc Surg
September 2025
Department of Epidemiology, Maastricht University, Maastricht, the Netherlands. Electronic address:
Objective: The current selection of patients for carotid revascularisation is mainly based on neurological symptoms and the degree of carotid artery stenosis. Individualised MRI based PRediction scOre using plaque Vulnerability for symptomatic carotid artEry disease patients (IMPROVE) can identify high risk patients who may benefit from carotid revascularisation, based on intraplaque haemorrhage, stenosis severity, cerebral symptoms, sex, and age. For use in clinical trials and eventual practice, the decision rule must be acceptable to clinicians.
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