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Article Abstract
We report a new method for examining changes in membrane permeability in dorsal root ganglion (DRG) cells under peripheral nerve injury conditions. By intravenously injecting YO-PRO-1, a monomeric cyanine nucleic acid stain, into rats with spared nerve injury (SNI), we observed the uptake of YO-PRO-1 in injured neurons and surrounding non-neuronal cells. This approach provides a tool for detecting in vivo DRG cell release activity in intact animals.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12296663 | PMC |
| http://dx.doi.org/10.17912/micropub.biology.001619 | DOI Listing |
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