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Although dopamine therapy is known to enhance creativity in some artists with Parkinson's disease (PD), similar creative changes have been observed in individuals with other neurological conditions, even without such treatment. This suggests that broader neurological and psychological factors beyond dopamine alone may influence creativity in PD. In this paper, I examined these influences through the lens of the : independence, curiosity, playfulness, confidence, openness, interdependence, and passion. Originally developed to support creativity in healthy individuals, the 7 Muses framework aligns closely with the structural and functional brain changes, as well as psychological shifts, commonly seen in PD. These changes may unlock latent creative potential, enabling PD artists to express themselves more authentically. By promoting a dynamic balance between top-down (goal-directed) and bottom-up (emotion-driven) processing across the creative cycle, preparation, imagination, and verification, PD-related changes may help reduce self-censorship, foster originality, and support the creation of meaningful, valuable work. Ultimately, beyond the effects of dopamine, some PD patients may awaken their dormant muses by following their intrinsic drives, listening more to their heart than their head.
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http://dx.doi.org/10.3934/Neuroscience.2025014 | DOI Listing |
Neurochem Res
September 2025
School of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang, 330004, China.
Metabolic synergy between astrocytes and neurons is key to maintaining normal brain function. As the main supporting cells in the brain, astrocytes work closely with neurons through intercellular metabolic synergy networks to jointly regulate energy metabolism, lipid metabolism, synaptic transmission, and cerebral blood flow. This important synergy is often disrupted in neurological diseases such as Alzheimer's disease, Parkinson's disease, and stroke.
View Article and Find Full Text PDFEur J Nucl Med Mol Imaging
September 2025
Nuclear Medicine and Molecular Imaging, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium.
Purpose: Cardiac noradrenergic denervation visualized by meta-[I]iodobenzylguanidine ([I]MIBG) imaging supports the diagnosis of Parkinson's disease (PD). Recently, meta-[F] fluorobenzylguanidine ([F]MFBG) PET demonstrated favorable imaging characteristics compared with [I]MIBG scintigraphy for neuroendocrine tumors. We assessed [F]MFBG dosimetry and myocardial pharmacokinetics in healthy controls and PD patients.
View Article and Find Full Text PDFCureus
August 2025
Internal Medicine, Jinnah Postgraduate Medical Centre, Karachi, PAK.
Neurodegenerative diseases and spinal cord injuries (SCI) pose a significant burden on the healthcare system globally. Diseases such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, and Huntington's disease precipitate cognitive, motor, and behavioral deficits. Parallelly, spinal cord injuries produce sensory and motor deficits, which are burdensome psychologically, socially, and economically.
View Article and Find Full Text PDFSmall
September 2025
Department of Materials Science and Engineering, Ludong University, Yantai, 264025, China.
With the continuous development of flexible sensors and flexible energy storage devices, gel materials with good flexibility, toughness, and tunable properties have attracted wide attention. Deep eutectic solvents (DES) have an obvious advantage of thermal and chemical stability over water. Therefore, eutectogels can effectively solve the problem of insufficient stability of traditional hydrogels.
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