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http://dx.doi.org/10.1007/s10071-025-01996-5 | DOI Listing |
Jpn J Ophthalmol
September 2025
Department of Ophthalmology, Osaka University Graduate School of Medicine, Room E7, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Abtract: PURPOSE: To evaluate the correlation between corneal backscatter and visual function in patients with Fuchs endothelial corneal dystrophy (FECD).
Study Design: Prospective case series.
Methods: This study included 53 eyes from 38 patients with FECD.
Int J Legal Med
September 2025
West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Ren Min Nan Road 3-17, P.O.Box: 610041, Chengdu, P. R. China.
The likelihood ratio (LR) is a recommended metric for assessing the strength of genetic information in relationship testing, one of the most important tasks in forensic science. LR calculation incorporate population frequencies, which is affected by population substructure. This study utilized population frequency data from 18 short tandem repeat (STR) loci across 13 Chinese populations, encompassing both majority and minority ethnic groups.
View Article and Find Full Text PDFTop Magn Reson Imaging
October 2025
BIOSPACE LAB, Nesles-la-Vallée, France.
Aims: Cardiac tumors are aggressive and asymptomatic in early stages, causing late diagnosis and locoregional metastasis. Currently, the standard of care uses gadolinium-based contrast agents for MRI, and the associated hypersensitivity reactions are a significant concern, such as gadolinium deposition disease. In addition, the proximity of cardiac lesions closer to vital structures complicates surgical interventions.
View Article and Find Full Text PDFZhonghua Yan Ke Za Zhi
September 2025
Ophthalmology Medical Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory for the Prevention and Treatment of Major Blinding Eye Diseases, Chongqing Branch (Municipality Division) of National Clinical Research Centre for Ocular Diseases, Chongqing 400016,
To explore optimized protocols for paraffin section preparation of the eyeball to enhance the histological visualization of key ocular structures. It was an experimental research, conducted from September 2022 to September 2024. The first experiment involved 18 porcine eyeballs, which were divided into five groups (six subgroups) by the random number table method.
View Article and Find Full Text PDFAm J Physiol Cell Physiol
September 2025
Department of Cell Biology, University of Pittsburgh, Pittsburgh, PA.
We previously demonstrated the CFTR correctors VX-445 (elexacaftor) and S-VX-121 (vanzacaftor) potentiate heterologously-expressed BK channels, as well as in primary human bronchial epithelial cells (HBEs). This potentiation of BK resulted in altered vasoreactivity and neuronal excitability. We postulated novel compounds could be identified that would potentiate BK while not affecting CFTR.
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