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Ultrasound (US) is a promising modality for wirelessly powering implantable devices, requiring encapsulated receivers to ensure long-term stability. Traditional hermetic packaging often limits acoustic transmission, making polymer-based encapsulation a more suitable alternative. This study investigates how implant-grade polymers, thermoplastic polyurethane (TPU), parylene-C, and medical-grade silicones (MED-1000 and MED2-4213), affect the receive performance of piezoelectric micromachined ultrasonic transducers (PMUTs). Simulations and measurements between 1 and 7 MHz show that all tested materials exhibit transmission coefficients above 94% at nanometer- and micrometer-scale thicknesses, confirming their acoustic transparency. The results show that although coated PMUTs are acoustically well matched with the surrounding water medium, the added mechanical load of the coating can hinder membrane motion and reduce the energy transferred to the PMUTs. Modeling and experimental data demonstrate that stiffer coatings, such as parylene-C, lead to a reduced sensitivity when similar thicknesses are used. Likewise, residual stress in materials like MED-1000 can also degrade the performance. These effects are not evident from acoustic transmission measurements alone, underscoring the need to assess both acoustic and mechanical properties when selecting encapsulation materials. In general, softer materials offer excellent acoustic performance for PMUT encapsulation, while stiffer materials must be applied in thinner layers to avoid impairing PMUT function.
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http://dx.doi.org/10.1109/TUFFC.2025.3592740 | DOI Listing |
JACC Heart Fail
September 2025
Université de Lorraine, Inserm, Centre d'Investigations Cliniques Plurithématique 1433, Centre Hospitalier Régional Universitaire de Nancy, Nancy, France.
JMIR Res Protoc
September 2025
National Institute of Public Health, University of Southern Denmark, Copenhagen K, Denmark.
Background: The high and increasing rate of poor mental health among young people is a matter of global concern. Experiencing poor mental health during this formative stage of life can adversely impact interpersonal relationships, academic and professional performance, and future health and well-being if not addressed early. However, only a few of those in need seek help.
View Article and Find Full Text PDFN Engl J Med
September 2025
Rwanda Biomedical Center, Kigali.
Background: On September 27, 2024, Rwanda reported an outbreak of Marburg virus disease (MVD), after a cluster of cases of viral hemorrhagic fever was detected at two urban hospitals.
Methods: We report key aspects of the epidemiology, clinical manifestations, and treatment of MVD during this outbreak, as well as the overall response to the outbreak. We performed a retrospective epidemiologic and clinical analysis of data compiled across all pillars of the outbreak response and a case-series analysis to characterize clinical features, disease progression, and outcomes among patients who received supportive care and investigational therapeutic agents.
Pain Med Case Rep
December 2023
Beth Israel Deaconess Medical Center, Department of Anesthesiology, Critical Care, and Pain Medicine, Harvard Medical School, Boston, MA.
Background: Spinal cord stimulation (SCS) is a minimally invasive neuromodulation treatment modality primarily used for failed back surgery syndrome (FBSS), complex regional pain syndrome, and diabetic neuropathy. Specifically, when utilized for the treatment of FBSS, placement can be complicated by the excessive scarring, adhesions, and altered anatomy limiting the access to the epidural space and advancement of the leads.
Case Report: Our patient is a 58-year-old woman with a history of scoliosis and severe lumbar spinal stenosis who presented for trial of an SCS for FBSS.
J Cataract Refract Surg
September 2025
Ophthalmology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.
Purpose: To compare the usability and training effectiveness of a 3D-printed coaxial illumination system mounted on an off-the-shelf stereo-microscope to a professional ophthalmic surgical microscope, in cataract surgery simulation.
Setting: Ophthalmology Lab, Ophthalmology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.
Design: Prospective randomized crossover study.