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Electrocardiographic (ECG) changes in myocardial infarction (MI) typically evolve predictably over time, allowing early identification of the ischemic territory and culprit vessel. Rarely, simultaneous ischemic changes in territories supplied by two different coronary arteries are observed, complicating diagnosis and urgent management. We present a rare case of acute chest pain with concurrent hyperacute T-waves in anterior leads, suggestive of left anterior descending (LAD) artery occlusion, and ST-segment elevations in inferior leads, suggestive of right coronary artery (RCA) occlusion. Coronary angiography revealed a chronic total occlusion of the RCA with retrograde filling from the LAD and an acute thrombotic lesion in the mid-LAD. Emergency percutaneous intervention in the LAD restored perfusion to both coronary beds, with rapid clinical and ECG recovery. This case highlights the importance of understanding ECG evolution in MI and emphasizes early revascularization strategies when facing diagnostic dilemmas.
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http://dx.doi.org/10.7759/cureus.86658 | DOI Listing |
Eur J Case Rep Intern Med
July 2025
Department of Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, USA.
Background: Thrombotic thrombocytopenic purpura (TTP) is a life-threatening hematologic emergency caused by ADAMTS13 deficiency, leading to microvascular thrombosis, haemolytic anaemia, thrombocytopenia, and end-organ damage. Neurological symptoms occur in up to 90% of cases and are frequently misdiagnosed as stroke. Prompt recognition and treatment reduce the mortality rate from over 90% to 10-20%.
View Article and Find Full Text PDFEur J Case Rep Intern Med
August 2025
Department of Internal Medicine, Dubai Hospital, Dubai Health, Dubai, Dubai, United Arab Emirates.
Introduction: Primary central nervous system vasculitis (primary CNS vasculitis) is a rare inflammatory disorder that affects small-to-medium-sized cerebral vessels, often leading to recurrent strokes. Diagnosis is vague due to non-specific neurological symptoms. Imaging findings, cerebrospinal fluid (CSF) analysis and exclusion of systemic vasculitis are essential for diagnosis.
View Article and Find Full Text PDFResearch (Wash D C)
September 2025
NHC Key Laboratory of Tropical Disease Control, School of Life Sciences and Medical Technology, Hainan Medical University, Haikou, Hainan 571199, China.
Aging is characterized by a gradual decline in the functionality of all the organs and tissues, leading to various diseases. As the global population ages, the urgency to develop effective anti-aging strategies becomes increasingly critical due to the growing severity of associated health problems. Immunotherapy offers novel and promising approaches to combat aging by utilizing approaches including vaccines, antibodies, and cytokines to target specific aging-related molecules and pathways.
View Article and Find Full Text PDFRSC Adv
September 2025
Instituto de Ciencia de Materiales de Madrid, ICMM-CSIC C/Sor Juana Inés de la Cruz, 3 Madrid 28049 Spain
Perovskite light-emitting diodes (PeLEDs) have emerged as a promising technology for next-generation display and lighting applications, thanks to their remarkable colour purity, tunability, and ease of fabrication. In this work, we explore the incorporation of plasmonic spherical nanoparticles (NPs) directly embedded into the green-emitting CsPbBr perovskite layer in a PeLED as a strategy to enhance both its optical and electrical properties. We find that plasmonic effects directly boost spontaneous emission while also influencing charge carrier recombination dynamics.
View Article and Find Full Text PDFIntroduction: is a spiral-shaped Gram-negative, enterohepatic bacterium classified as a conditional pathogen (pathogenicity group 2). It is known to cause bacteremia and a variety of other diseases in humans. In particular, has been shown to impair intracellular cholesterol metabolism when interacting with macrophages, leading to foam cell formation.
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