Changes in potential pathogenicity-associated proteins of upon infection of macrophage cells.

Introduction: is a spiral-shaped Gram-negative, enterohepatic bacterium classified as a conditional pathogen (pathogenicity group 2). It is known to cause bacteremia and a variety of other diseases in humans. In particular, has been shown to impair intracellular cholesterol metabolism when interacting with macrophages, leading to foam cell formation.

Phage Banzai: Genomic and Functional Analysis of Novel with Lytic Activity Against .

Antibiotic-resistant presents a critical global health challenge, particularly in hospital-acquired infections. Bacteriophages offer a promising therapeutic avenue due to their ability to target and lyse resistant strains. This study characterizes phage Banzai, a newly isolated (family ) with lytic activity against multiple isolates, including multidrug-resistant strains.

HS-GC-MS Method for the Diagnosis of IBD Dynamics in a Model of DSS-Induced Colitis.

Inflammatory bowel disease (IBD) is highly prevalent globally and, in the majority of cases, remains asymptomatic during its initial stages. The gastrointestinal microbiota secretes volatile organic compounds (VOCs), and their composition alters in IBD. The examination of VOCs could prove beneficial in complementing diagnostic techniques to facilitate the early identification of IBD risk.

Proteogenomic annotation of T6SS components identified in secretome.

Introduction: (Bf)'s T6SS locus has been characterized and shown to have functional activity in competition experiments. It has been demonstrated that symbiont nontoxigenic Bf strains have a more effective "weapon" effect on pathogenic Bf, which is realized through the activity of effector-immune (E-I) protein pairs. Intensive study of the T6SS structure has led to an understanding of certain issues related to its functional activity, but the exact regulatory mechanisms of E-I protein pair activity remain unclear.

Parabacteroides absconsus sp. nov., isolated from feces of a child with atopic dermatitis.

An obligate anaerobic, Gram-negative rod-shaped bacterial strain designated AD58 was isolated from the feces of a 3-year-old boy with atopic dermatitis. The closest species is Parabacteroides fecalis with 96.98% 16S rRNA gene identity.