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Purpose: StarGuide (GE HealthCare, Haifa, Israel), a full-ring SPECT/CT system using Cadmium Zinc Telluride (CZT) technology, allows detectors to perform a pendulum motion (sweep) during SPECT acquisition. It offers two sweep modes: continuous and step and shoot, and we investigated the impact of different sweep modes on spatial resolution and image uniformity.
Methods: Spatial resolution was evaluated using the full width half maximum (FWHM) of line source images. Image uniformity was assessed using the root mean square uniformity (%RMSU) of pool phantom images. Image reconstruction was performed using the 3D-OSEM method. Attenuation correction and spatial resolution correction were applied, and no filters were used during the reconstruction process.
Results: FWHM at the center of rotation with update 500 was 5.60±0.13 mm for continuous and 4.40±0.15 mm for step and shoot. %RMSU with update 100 was 8.94±0.38% for continuous and 9.23±0.35% for step and shoot.
Conclusion: Using the step-and-shoot sweep mode can maintain high spatial resolution.
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http://dx.doi.org/10.6009/jjrt.25-1542 | DOI Listing |
Methods Appl Fluoresc
September 2025
Department of Biotechnology and Biophysics, University of Würzburg, Department of Biotechnology & Biophysics, Wuerzburg University, Am Hubland, Wuerzburg, other, 97074, GERMANY.
Super-resolution microscopy (SRM) has revolutionized fluorescence imaging enabling insights into the molecular organization of cells that were previously unconceivable. Latest developments now allow the visualization of individual molecules with nanometer precision and imaging with molecular resolution. However, translating these achievements to imaging under physiological conditions in cells remains challenging.
View Article and Find Full Text PDFACS Appl Mater Interfaces
September 2025
Leibniz-Institut für Katalyse e.V. (LIKAT), Albert-Einstein-Str. 29a, Rostock 18059, Germany.
Metal-organic frameworks (MOFs) are transformative platforms for heterogeneous catalysis, but distinguishing atomically dispersed metal sites from subnanometric clusters remains a major challenge. This often demands the integration of multiple characterization techniques, many of which either lack the resolving power to distinguish active sites from their surrounding environments (e.g.
View Article and Find Full Text PDFPhytomedicine
August 2025
Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China. Electronic address:
Background: Traditional Chinese medicines (TCMs) have a long-standing history and diverse applications. However, their complex multi-component compositions and intricate mechanisms of action pose significant challenges for modern scientific investigation. Addressing these complexities requires advanced techniques capable of dissecting cellular and molecular interactions with high resolution.
View Article and Find Full Text PDFNeurol Med Chir (Tokyo)
September 2025
Department of Neurosurgery, Keio University School of Medicine.
Skull base surgery requires precise spatial recognition; however, existing educational tools remain limited. To address this issue, we developed a step-by-step stereotactic three-dimensional anatomical model of the anterior transpetrosal approach using digital photogrammetry. Cadaveric dissection was subsequently performed in 17 steps, of which 10 were reconstructed into three-dimensional models.
View Article and Find Full Text PDFSci Total Environ
September 2025
Department of Geological Sciences and Geological Engineering, Queen's University, 99 University Ave, K7L 3N6 Kingston, Ontario, Canada.
Hyperspectral data have been overshadowed by multispectral data for studying algal blooms for decades. However, newer hyperspectral missions, including the recent Plankton, Aerosol, Cloud, ocean Ecosystem (PACE) Ocean Color Instrument (OCI), are opening the doors to accessible hyperspectral data, at spatial and temporal resolutions comparable to ocean color and multispectral missions. Simulation studies can help to understand the potential of these hyperspectral sensors prior to launch and without extensive field data collection.
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