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Impaired lymphatic circulation in the mediastinum may result from congenital disorders, leakage secondary to trauma, or infiltration by neoplasia. It manifests as chylothorax, plastic bronchitis, and/or alveolar fatty pneumonitis. Lymphography, involving the injection of contrast medium into peripheral lymph nodes, was previously utilised but posed challenges in execution and image interpretation. We describe two patients admitted to our department with relapsing chylothorax and respiratory failure associated with "fatty" pneumonitis and plastic bronchitis. The final diagnosis was confirmed by injecting 2 mL of gadolinium into the mediastinal lymph nodes under endoscopic ultrasonography guidance (EBUS), and magnetic resonance imaging (MRI) visualised its distribution.
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http://dx.doi.org/10.36141/svdld.v42i2.16539 | DOI Listing |
Pharmacotherapy
September 2025
Division of Pediatric Cardiology, Department of Pediatrics, University of Michigan Health System, Ann Arbor, Michigan, USA.
Introduction: Pediatric plastic bronchitis (PB) is a rare complication of surgically palliated congenital heart disease (CHD). Fibrin casts obstruct airways and can cause respiratory distress. There are no therapeutics approved by the United States Food and Drug Administration to treat PB, but inhaled tissue plasminogen activator (tPA) has been anecdotally used to relieve symptoms.
View Article and Find Full Text PDFCirc Cardiovasc Interv
September 2025
Division of Cardiology (Y.D., E.P., L.B., M.J.G., R.C., J.T., M.L.O.B., D.V., A.G.D.W., E.F., R.S., J.J.R., C.L.S.), Children's Hospital of Philadelphia, PA.
Background: External drainage of the thoracic duct can temporarily reduce tissue congestion and improve symptoms in patients with heart failure. However, loss of fluid limits the duration of this approach. Here, we report on our initial experience with thoracic duct drainage and autotransfusion in patients with elevated central venous pressure.
View Article and Find Full Text PDFJ Formos Med Assoc
September 2025
Department of Pediatrics, Peking University International Hospital, Beijing, China. Electronic address:
Pediatr Dermatol
August 2025
Department of Dermatology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.
An 8-year-old female developed fever, dyspnea, and cough 1 week after starting ustekinumab for psoriasis. She was noted to have recurrent left lower lobe consolidation and subsequent obstructing eosinophilic casts and was diagnosed with eosinophilic plastic bronchitis. Her respiratory symptoms improved with systemic steroids, mepolizumab for 10 months, and discontinuing ustekinumab.
View Article and Find Full Text PDFBMC Infect Dis
August 2025
Department of Pediatrics, The First Affiliated Hospital of Xinxiang Medical University, No.88 of JianKang Road, Weihui, Henan province, 453100, China.
Objective: To explore the clinical characteristics and independent risk factors of pneumococcal pneumonia complicated with plastic bronchitis.
Methods: 156 patients with pneumococcal pneumonia who were admitted to the Department of Pediatrics of the First Affiliated Hospital of Xinxiang Medical University. The patients were divided into plastic bronchitis (PB) group and non-plastic bronchitis (non-PB) group.