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Background: Understanding personal beliefs about medications is an effective approach to improving adherence. A validated tool is essential for identifying these beliefs in routine clinical practice.
Objective: To validate the factor structure and reliability of the Traditional Chinese version of the Beliefs about Medicines Questionnaire-Specific (BMQ-Specific) among individuals with type 2 diabetes (T2D) in Taiwan.
Methods: The original 10-item BMQ-Specific was translated into Traditional Chinese using a forward-backward translation process and reviewed by four experts in pharmacy practice and educational psychology. A cross-sectional study was conducted among adults with T2D who were using diabetes medications. Participants were recruited from five community pharmacies in Taiwan between June 2023 and May 2024. Internal consistency was assessed using McDonald's omega (ω). Construct validity was examined through exploratory factor analysis, and criterion validity was determined by exploring associations between concern beliefs, medication adherence, and glycemic control, as measured by A1C levels.
Results: Two hundred and seventy-three patients participated in the study. Exploratory factor analysis confirmed a two-factor structure consistent with the original English version, comprising the Specific-Necessity and Specific-Concerns subscales. All items loaded onto their respective subscales. The internal consistency reliability of the instrument was acceptable, with McDonald's ω values of 0.785 for both the BMQ-Specific Necessity and BMQ-Specific Concerns subscales. These satisfactory properties were further supported by predictive validity data, which demonstrated the impact of treatment beliefs on adherence levels. The BMQ-Specific Concerns subscale showed a positive correlation with higher barriers to medication-taking (r = 0.270, p < 0.001) and poorer glycemic control (r = 0.130, p = 0.032).
Conclusion: The Traditional Chinese BMQ-Specific is a reliable and valid tool for assessing medication beliefs among patients with T2D in Taiwan. It can be effectively incorporated into clinical practice to support patient-provider communication and improve medication adherence.
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http://dx.doi.org/10.2147/PPA.S531219 | DOI Listing |
Eur J Prev Cardiol
September 2025
Department of Nursing, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China.
JAMA Netw Open
September 2025
Division of Cardiology, Department of Internal Medicine, New Taipei Municipal TuCheng Hospital, New Taipei, Taiwan.
Importance: The cardiovascular benefits of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) may vary by body mass index (BMI), but evidence on BMI-specific outcomes remains limited.
Objective: To investigate the associations of GLP-1 RA use with cardiovascular and kidney outcomes across BMI categories in patients with type 2 diabetes.
Design, Setting, And Participants: This retrospective cohort study used the Chang Gung Research Database, a clinical dataset covering multiple hospitals in Taiwan.
Neurochem Res
September 2025
International Translational Neuroscience Research Institute, Zhejiang Chinese Medical University, Hangzhou, 310053, Zhejiang, China.
The concept of the central nervous system (CNS) reserve emerged from the mismatch often observed between the extent of brain pathology and its clinical manifestations. The cognitive reserve reflects an "active" capacity, driven by the plasticity of CNS cellular components and shaped by experience, learning, and memory processes that increase resilience. We propose that neuroglial cells are central to defining this resilience and cognitive reserve.
View Article and Find Full Text PDFArch Microbiol
September 2025
School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Endophytic fungi are nonpathogenic fungi that live symbiotically in the interior of healthy plant tissues and form mutualistic associations with their hosts. These fungi are critically involved in promoting plant development, strengthening plant uptake of nutrients, and improving plant resistance to biotic and abiotic stress conditions. Endophytic fungi improve plant growth by synthesizing phytohormones (e.
View Article and Find Full Text PDFNeuroradiology
September 2025
Department of Radiology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Purpose: To develop and validate an integrated model based on MR high-resolution vessel wall imaging (HR-VWI) radiomics and clinical features to preoperatively assess periprocedural complications (PC) risk in patients with intracranial atherosclerotic disease (ICAD) undergoing percutaneous transluminal angioplasty and stenting (PTAS).
Methods: This multicenter retrospective study enrolled 601 PTAS patients (PC+, n = 84; PC -, n = 517) from three centers. Patients were divided into training (n = 336), validation (n = 144), and test (n = 121) cohorts.