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http://dx.doi.org/10.1007/s00068-025-02938-z | DOI Listing |
Transplant Cell Ther
September 2025
Department of Pediatrics, University of Arizona, Tucson, AZ, USA; Banner University Medical Center, Tucson, AZ, USA; BIO5 Institute, University of Arizona, Tucson, AZ, USA; The University of Arizona Cancer Center, Tucson, AZ, USA; Department of Immunobiology, University of Arizona, Tucson, AZ, USA;
Background: Allogeneic hematopoietic cell transplantation (allo-HCT) is a potentially curative treatment for pediatric patients with hematologic malignancies. Human leukocyte antigen (HLA)-matched sibling donors (MSDs) are considered the optimal source for stem cell transplantation; however, up to 70% of patients lack an MSD. This disparity is particularly pronounced among racial and ethnic minorities, who face challenges in identifying matched unrelated donors (MUDs).
View Article and Find Full Text PDFTransplant Cell Ther
September 2025
Division of Hematology and Clinical Laboratory Medicine, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University, Yonago, Japan. Electronic address:
Primary plasma cell leukemia (pPCL) is a rare and aggressive subtype of plasma cell malignancy. Although hematopoietic stem cell transplantation (HCT), including autologous HCT (auto-HCT) and allogeneic HCT (allo-HCT), is widely used, an optimal treatment strategy is undetermined. We retrospectively analyzed patients with pPCL who underwent HCT between 2006 and 2022 in Japan using Japanese registry data.
View Article and Find Full Text PDFPhys Med Biol
September 2025
BioMaps, Université Paris-Saclay, CNRS, Inserm, SHFJ, CEA, 4 Place du général Leclerc, Orsay, Île-de-France, 91401, FRANCE.
Deep learning has shown great promise for improving medical image reconstruction, including PET. However, concerns remain about the stability and robustness of these methods, especially when trained on limited data. This work aims to explore the use of the Plug-and-Play (PnP) framework in PET reconstruction to address these concerns.
View Article and Find Full Text PDFPhys Rev Lett
August 2025
Peng Huanwu Center for Fundamental Theory, Hefei, Anhui 230026, China.
We study nonperturbative effects of torus partition function of the TT[over ¯]-deformed 2D conformal field theory (CFT) by resurgence in this Letter and a companion paper. The deformed partition function can be written as an infinite series of the deformation parameter λ. We develop highly efficient methods to compute perturbative coefficients in the λ expansion.
View Article and Find Full Text PDFPLoS One
September 2025
Institute of Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada.
Achieving optimal alignment and fit is a key aspect of ankle-foot orthosis (AFO) design, as it directly influences the effectiveness of the device. While digital workflows offer the potential to integrate quantifiable alignment measures and corrections into AFO design, a major challenge remains in controlling lower-limb positioning and alignment during 3D scanning. This study aimed to evaluate pediatric AFO alignment and shape differences of directly scanned (live scan) vs casted lower limb models.
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