Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Diabetic neuropathy (DN) is a prevalent chronic complication of diabetes. Sweat glands are directly controlled by the sympathetic nervous system, whose neuropathy affects the thermal regulation of the skin and results in morphological changes in sweat ducts. This study aims to investigate the correlation between the characteristics of fingerprint-guided sweat ducts assessed by optical coherence tomography and DN based on a predictive model using a back propagation neural network (BPNN) and principal component analysis (PCA). The results demonstrate that the number, volume, and spacing of sweat ducts are correlated with the severity of DN. The Voronoi diagram of the sweat duct distribution demonstrates irregularities in the spatial distribution among patients with DN. Furthermore, the PCA-based BPNN model has good predictive accuracy between patients with non-neuropathic, neuropathic, and severe neuropathic diabetes. These findings suggest that OCT-assessed sweat duct features may serve as non-invasive biomarkers for DN in patients with diabetes.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/jbio.202500096 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Management of intrahepatic cholangiocarcinoma in a patient with Caroli's disease: a case report and literature review.
J Surg Case Rep
August 2025
Department of Surgery (A), Heinrich-Heine-University, Medical Faculty and University Hospital Duesseldorf, Moorenstr. 5, 40225 Duesseldorf, North Rhine-Westphalia, Germany.
Caroli's disease is a rare congenital disorder characterized by cystic dilatations of the intrahepatic bile ducts, often leading to recurrent bacterial cholangitis, biliary lithiasis, and cirrhosis. In 7%-16% of cases, it progresses to intrahepatic cholangiocarcinoma, emphasizing the need for early diagnosis and intervention. This report presents a 56-year-old patient with recurrent upper abdominal pain, chronic fatigue, and night sweats.
View Article and Find Full Text PDFAn Adult-Onset Case of Porokeratotic Eccrine Ostial and Dermal Duct Nevus (PEODDN) in a Previously Healthy 28-Year-Old Indian Male: A Case Report.
Cureus
July 2025
Dermatology, Al Jahra Hospital, Al Jahra, KWT.
A 28-year-old Indian male with no previous medical or dermatological history presented with mildly pruritic linear skin lesions over the right anterior chest and arm. The lesions had been gradually progressing over the course of six years. Examination revealed multiple confluent, reddish-brown papules following Blaschko's lines, along with punctate hyperkeratotic papules over the right hand, with sparing of the mucosa, scalp, and nails.
View Article and Find Full Text PDFCFTR Gene Regulation in Human Pancreatic Duct, Bile Duct and Sweat Gland Epithelial Cells.
J Cell Mol Med
August 2025
Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Epithelial cells at many sites in the body are affected by the inherited disorder cystic fibrosis (CF). The lung was the major focus of research until recently, when effective therapeutics became available for most people with CF. There is now renewed interest in CF aetiology in other locations in the body, where the regulatory mechanisms for the CF transmembrane conductance regulator (CFTR) gene are less well-characterised.
View Article and Find Full Text PDFThe modeling of the interaction of pulsed 5G/6G signals and the fine structure of human skin.
Sci Rep
August 2025
Department of Physics, Ariel University, Ariel, 407000, Israel.
Current regulations concerning the allowed levels of human exposure to electromagnetic radiation emanating from wireless technologies are governed by the Specific Absorption Rate standard (SAR). This allows the absorption by tissue of up to 2 W/kg averaged for 6 minutes in a 10 g cube of homogenized tissue. Much criticized, the SAR standard relates only to thermal effects.
View Article and Find Full Text PDFCorrelation Between Fingerprint-Guided Sweat Ducts Features From OCT and Diabetic Neuropathy Using Voronoi Diagram.
J Biophotonics
July 2025
Key Laboratory of Optoelectronic Science and Technology for Medicine, Ministry of Education, Fujian Provincial Key Laboratory of Photonics Technology, Fujian Provincial Engineering Technology Research Center of Photoelectric Sensing Application, College of Photonic and Electronic Engineering, Fujian
Diabetic neuropathy (DN) is a prevalent chronic complication of diabetes. Sweat glands are directly controlled by the sympathetic nervous system, whose neuropathy affects the thermal regulation of the skin and results in morphological changes in sweat ducts. This study aims to investigate the correlation between the characteristics of fingerprint-guided sweat ducts assessed by optical coherence tomography and DN based on a predictive model using a back propagation neural network (BPNN) and principal component analysis (PCA).
View Article and Find Full Text PDF