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Background: Prenatal diagnosis of esophageal atresia remains challenging, with indirect signs such as polyhydramnios, a small or absent stomach bubble, and a dilated upper esophageal pouch often inconsistently present. Only 10-40% of EA cases are diagnosed prenatally. Fetal MRI can overcome ultrasound limitations; however, constraints like motion can hinder evaluation of the esophagus.
Methods: Super-resolution imaging with slice-to-volume reconstruction (SVR) is one approach that can improve image quality. This technique generates high-resolution 3D images from standard fetal MRI slices to enhance diagnostic accuracy.
Aim: We present the application of super-resolution imaging with SVR to accurately diagnose EA and assess the presence or absence tracheoesophageal fistulas.
Conclusion: This technique demonstrates significant potential for accurately delineating the relevant surgical anatomy, which can improve surgical planning.
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http://dx.doi.org/10.1007/s00247-025-06309-z | DOI Listing |
Acta Obstet Gynecol Scand
September 2025
Unit of Gynecological Oncology, Department of Oncology, KU Leuven, Leuven, Belgium.
Introduction: Vulvovaginal cancer in pregnancy is rare. Limited data complicate decision-making and patient counseling. Our review, coupled with new case data, fills a current gap in the literature and provides practical insights.
View Article and Find Full Text PDFStroke
September 2025
Division of Neonatology, Department of Pediatrics, Willem-Alexander Children's Hospital, Leiden University Medical Center, the Netherlands. (B.O.v.O., M.R., M.S.S., E.L., L.S.d.V., S.J.S.).
Background: Monochorionic twins, characterized by placental sharing and vascular anastomoses, carry a high risk of brain injury, including perinatal arterial ischemic stroke (PAIS). However, the pathophysiology and timing-related risk factors of PAIS remain unclear.
Methods: Retrospective cohort of all monochorionic twins with neuroimaging-confirmed PAIS born from 2005 to 2024 and evaluated at a Dutch national referral center.
Rev Cardiovasc Med
August 2025
The Heart Institute, Department of Pediatrics, University of Tennessee Health and Science Center, Memphis, TN 38103, USA.
Left ventricular noncompaction (LVNC), also called noncompaction cardiomyopathy (NCM), is a myocardial disease that affects children and adults. Morphological features of LVNC include a noncompacted spongiform myocardium due to the presence of excessive trabeculations and deep recesses between prominent trabeculae. Incidence and prevalence rates of this disease remain contentious due to varying clinical phenotypes, ranging from an asymptomatic phenotype to fulminant heart failure, cardiac dysrhythmias, and sudden death.
View Article and Find Full Text PDFEur Radiol Exp
September 2025
Center for MR-Research, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland.
Background: Fetal MRI is increasingly used to investigate fetal lung pathologies, and super-resolution (SR) algorithms could be a powerful clinical tool for this assessment. Our goal was to investigate whether SR reconstructions result in an improved agreement in lung volume measurements determined by different raters, also known as inter-rater reliability.
Materials And Methods: In this single-center retrospective study, fetal lung volumes calculated from both SR reconstructions and the original images were analyzed.
Eur Heart J Cardiovasc Imaging
September 2025
Department of Diagnostic and Interventional Radiology, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Aims: Fetal circulation undergoes complex changes in congenital heart disease (CHD) that are challenging to assess with fetal echocardiography. This study aimed to assess clinical feasibility and diagnostic value of 4D flow cardiac magnetic resonance (CMR) in fetal CHD.
Methods And Results: Pregnant women in advanced third trimester pregnancy with fetal CHD were prospectively recruited for fetal CMR between 08/2021 and 11/2024.