[Analysis on detection rate of thyroid nodule and influencing factors in children and adolescents in Jiangsu Province].

To evalaute the prevalence and determinants of thyroid nodules in children and adolescents in Jiangsu Province. This study included in-school students aged 8-17 years and selected through stratified cluster random sampling in Jiangsu. Thyroid nodule was diagnosed when its diameter was ≥3 mm. Random urine samples were collected for the detection of urinary iodine concentration with arsenic-cerium catalytic spectrophotometry. Data were analyzed by using test and logistic regression model. In the 8 201 children and adolescents selected, the thyroid nodule detection rate was 16.10%. Multivariate logistic regression analysis revealed that, compared with those with urinary iodine levels of 100-299 μg/L, boys, those with normal body weight, those who were satisfied with their school performance, urinary iodine concentration ≥300 μg/L (=1.15, 95%: 1.01-1.31), being girls (=1.42, 95%: 1.26-1.60), being overweight (=1.27, 95%: 1.07-1.50), being obese (=1.23, 95%: 1.03-1.47), and dissatisfied with school performance (=1.22, 95%: 1.04-1.43) were associated with higher likelihood of thyroid nodule detection. Children and adolescents who had solid snacks 2 times per week to 2 times per month (=0.86, 95%: 0.74-0.99) or less than 2 times per month (=0.80, 95%: 0.68-0.93) were more likely to have lower detection rate compared with those who had solid snacks more than 2 times per week. The detection rate of thyroid nodule increased with age (=1.09, 95%: 1.06-1.11). The main factors influencing the detection rate of thyroid nodule in children and adolescents aged 8-17 years in Jiangsu included gender, age, urinary iodine concentration, BMI, self-assessed school performance and dietary habit.