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This study investigates radiofrequency ablation (RFA) parameters for varicose vein treatment using a three-dimensional mathematical model operating at 470 kHz. The model evaluates how power settings, temperature thresholds, blood flow velocity, and electrode spacing influence therapeutic efficacy and tissue safety. Findings demonstrate that higher power and temperature settings, combined with lower blood flow rates, enhance venous wall heating while minimizing extraluminal tissue damage. Stagnant blood flow optimizes thermal energy delivery, and adjusting electrode spacing reduces the required number of ablations. Temperature-controlled radiofrequency ablation has a controlled electrode temperature for better temperature delivery. This study provides actionable guidance for clinicians to tailor RFA protocols that emphasize management and electrode configuration adjustments for safer and more efficient outcomes in varicose vein treatment.
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http://dx.doi.org/10.1080/15368378.2025.2534380 | DOI Listing |
J Cardiovasc Electrophysiol
September 2025
Department of Internal Clinical, Aenesthesiological, and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy.
Cardiovasc Intervent Radiol
September 2025
Radiology Department, Casa Di Cura San Francesco, Via IV Novembre 7, 24128, Bergamo, Italy.
Heart Rhythm
September 2025
Translational Cardiology Group, Health Research Institute, Santiago de Compostela, Spain; CIBERCV, Madrid, España. Electronic address:
Background: High % of low-voltage area (LVA), a surrogate of scar, is associated with atrial fibrillation (AF) recurrence after pulmonary vein isolation (PVI). Noninvasive biomarkers of LVA are a medical need for PVI decision.
Objective: We aimed to identify the proteome profile of plasma extracellular vesicles (EVs) associated with high % LVA, their cellular origin, and their regulation by hyperglycemia.
Equine Vet J
September 2025
Equine Cardioteam Ghent, Department of Internal Medicine, Reproduction and Population Medicine, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
Background: Frequent premature atrial complexes (PACs) can increase the risk of atrial fibrillation or atrial tachycardia, and pharmacological therapy can be challenging.
Objective: To report the use of three-dimensional electro-anatomical mapping of PAC originating from the right atrial free wall and treatment by radiofrequency ablation in three horses.
Study Design: Retrospective case report.
Arch Esp Urol
August 2025
Department of Urology, Izmir Katip Celebi University, 35160 Izmir, Turkey.
Background: Benign prostatic hyperplasia (BPH) is a common condition, particularly among high-risk patients who are unsuitable for surgical intervention due to comorbidities or anticoagulant use. Bipolar radiofrequency ablation is a minimally invasive technique that has been studied for its potential safety and efficacy. This study aimed to investigate the effectiveness of bipolar radiofrequency ablation in treating BPH and to identify the factors influencing the procedural success in high-risk patients.
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