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A 15-year-old post-REV patient underwent transcatheter pulmonary valve replacement with a 23 mm SAPIEN 3 for right ventricular outflow tract (RVOT) stenosis and severe regurgitation. At 9 months, recurrent stenosis revealed multiple frame fractures. Balloon redilation up to 24 mm was limited by aortic root compression and recoil, prompting surgery. This first reported case of early SAPIEN 3 fracture in the pulmonary position highlights structural risks in complex RVOT anatomies.
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http://dx.doi.org/10.1002/ccd.70010 | DOI Listing |
PLoS One
September 2025
Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Seoul, Korea.
Volumetric modulated arc therapy (VMAT) for lung cancer involves complex multileaf collimator (MLC) motion, which increases sensitivity to interplay effects with tumour motion. Current dynamic conformal arc methods address this issue but may limit the achievable dose distribution optimisation compared with standard VMAT. This study examined the clinical utility of a VMAT technique with monitor unit limits (VMATliMU) to mimic conformal arc delivery and reduce interplay effects while maintaining plan quality.
View Article and Find Full Text PDFJ Appl Physiol (1985)
September 2025
Ludwig Engel Centre for Respiratory Research, Westmead Hospital, Sydney, NSW, Australia.
Lung volume change modifies pharyngeal airway patency by altering breathing-related passive force transmission between lower and upper airways (via tracheal and other connections). We hypothesise that such force transmission may also impact active upper airway dilator muscle function by altering resting muscle length. The aim of this study was to determine the relationship between end expiratory lung volume (EELV) and ability of sternohyoid muscle (SH) contraction to alter pharyngeal airway patency.
View Article and Find Full Text PDFJ Robot Surg
September 2025
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, UT Health San Antonio, 7703 Floyd Curl Drive, 7836, San Antonio, TX, 78229-3900, USA.
To evaluate intraoperative ventilatory mechanics during robotic-assisted hysterectomy in obese women with endometrial cancer and introduce the concept of a physiologic "ceiling effect" in respiratory strain. We conducted a retrospective cohort study of 89 women with biopsy-confirmed endometrial cancer who underwent robotic-assisted total hysterectomy between 2011 and 2015. Intraoperative ventilatory parameters, including plateau airway pressure and static lung compliance, were recorded at five-minute intervals.
View Article and Find Full Text PDFJTCVS Open
August 2025
Department of Thoracic Surgery, Hull University Teaching Hospitals, Hull, United Kingdom.
Objective: The underrepresentation of women in thoracic surgery has been well described worldwide. Women can serve as role models for trainees and advance their careers through academic appointments, leadership positions, and involvement in thoracic societies. We aimed to characterize differences between representation of women in thoracic surgery in the United States and Europe.
View Article and Find Full Text PDFJTCVS Open
August 2025
Department of Anaesthesia and Intensive Care Medicine, Royal Papworth Hospital, Cambridge Biomedical Campus, Cambridge, United Kingdom.
Objective: Postoperative intraluminal thrombosis after frozen elephant trunk replacement has been reported to occur with a frequency of 6% to 17% and is associated with poor outcomes. The purpose of this institutional review is to analyze thrombosis rate, predisposing patient and operative factors, and assess different anticoagulation regimens.
Methods: This retrospective cohort study includes 174 patients operated on over 10 years.