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Traditional wearable ultrasound devices pose challenges concerning the rigidity and environmental impact of lead-based piezoelectric materials. This study proposes a silicon nanocolumn capacitive micromachined ultrasonic transducer (snCMUT) array for real-time wearable ultrasound imaging in disposable patches. Using a lead-free design, snCMUT incorporates silicon nanocolumns to address existing issues and achieves high transmission efficiency (220 kPa/V), flexibility, and low power consumption. The specialized structure of snCMUT enhances displacement efficiency, enabling high-resolution imaging while maintaining a thin, flexible form factor (~900 μm). Phantom imaging demonstrates its superior performance, with high axial and lateral resolutions (0.52 and 0.55 mm) and depth penetration (~70 mm) at low voltage (8.9 V). Upon successful application to monitor both sides of the human carotid arteries, snCMUT offers clear ultrasound images and continuous blood pressure waveform monitoring. This proposed innovation presents significant potential for continuous medical imaging and cardiovascular health assessment, addressing environmental concerns and reducing manufacturing costs (<$20).
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http://dx.doi.org/10.1038/s41467-025-61903-x | DOI Listing |
Int J Sport Nutr Exerc Metab
September 2025
Mary MacKillop Institute for Health Research, Australian Catholic University, Melbourne, VIC, Australia.
Technological innovations can provide cyclists and their support team additional data. These data have potential to improve understanding of performance determinants and could be used to identify and tailor nutritional strategies to improve cycling performance. This potential, however, is dependent on the quality, interpretation, and practical use of the data generated.
View Article and Find Full Text PDFSci Adv
September 2025
State Key Laboratory for Manufacturing System Engineering, State Industry-Education Integration Center for Medical Innovations, International Joint Laboratory for Micro/Nano Manufacturing and Measurement Technologies, Shaanxi Innovation Center for Special Sensing and Testing Technology in Extreme En
Continuous monitoring of cardiovascular vital signs can reduce the incidence and mortality of cardiovascular diseases, yet cannot be implemented by current technologies because of device bulkiness and rigidity. Here, we report self-adhesive and skin-conformal ultrasonic transducer arrays that enable wearable monitoring of multiple hemodynamic parameters without interfering with daily activities. A skin-adaptive focused ultrasound method with rational array design is proposed to implement measurement under wide ranges of skin curvatures and depths with improved sensing performances.
View Article and Find Full Text PDFMikrochim Acta
September 2025
Faculty of Science, Shenyang University of Chemical Technology, Shenyang, 110142, China.
A sensitive electrochemical glucose biosensor using ZrO₂@CNTs nanocomposite was developed for real-time metabolism monitoring for athletes. The nanocomposite was prepared by a simple ultrasound-assisted technique, and the glucose oxidase (GOx) was covalently immobilized to improve the biorecognition ability. CNTs treated with acid served as a highly conductive framework, and ZrO₂ nanoparticles can provide structural stability and catalytic performance, thus showing synergistic enhancement of electron transfer kinetics and enzyme loading capacity.
View Article and Find Full Text PDFEmerg Top Life Sci
September 2025
Hurdle.bio / Chronomics Ltd., London, UK.
Artificial intelligence (AI) is transforming many fields, including healthcare and medicine. In biomarker discovery, AI algorithms have had a profound impact, thanks to their ability to derive insights from complex high-dimensional datasets and integrate multi-modal datatypes (such as omics, electronic health records, imaging or sensor and wearable data). However, despite the proliferation of AI-powered biomarkers, significant hurdles still remain in translating them to the clinic and driving adoption, including lack of population diversity, difficulties accessing harmonised data, costly and time-consuming clinical studies, evolving AI regulatory frameworks and absence of scalable diagnostic infrastructure.
View Article and Find Full Text PDFProg Mol Biol Transl Sci
September 2025
Department of Systems and Computer Engineering, Carleton University, Ottawa, ON, Canada. Electronic address:
Monitoring skeletal muscle contraction provides valuable information about the muscle mechanical properties, which can be helpful in various biomedical applications. This chapter presents a single-element flexible and wearable ultrasonic sensor (WUS) developed by our research group and its application for continuously monitoring and characterizing skeletal muscle contraction. The WUS is made from a 110-µm thick polyvinylidene fluoride piezoelectric polymer film.
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