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This study investigates bubbly flow in a rectangular open channel under microgravity. A homogeneous flow model is used to compute frictional pressure loss and then establish a correlation between the drag coefficient and mass quality, leading to a one-dimensional model of free surface bubbly flow. Furthermore, the homogeneous flow model is integrated into computational fluid dynamics simulations, which align closely with experimental observations. The theoretical model and simulations show a strong concordance, with a critical flow rate determined through calculations exhibiting an average relative error of 4.93%. The findings reveal a positive correlation between mass quality and critical flow rate; increasing mass quality enhances the critical flow rate and stabilizes the free surface but reduces the liquid phase's flow efficiency. This research contributes to the theoretical understanding of microgravity free surface flow.
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http://dx.doi.org/10.1038/s41526-025-00496-7 | DOI Listing |
Chem Commun (Camb)
September 2025
Inorganic Chemistry I Institute, Ruhr-Universität Bochum, Universitätsstrasse 150, 44801 Bochum, Germany.
Herein, we report a solid-state polycyclotrimerization of 1,4-diethynylbenzene using mechanochemical activation in a ball mill, yielding a highly porous and hydrophobic hyperbranched polymer (HBP) with a specific surface area of up to 570 m g. The reaction, catalyzed by Fe(hmds) and conducted under solvent-free conditions, was optimized by varying milling time and frequency. This method enables the efficient synthesis of insoluble, porous organic polymers with high yields (up to 95%) and offers an environmentally friendly alternative to traditional solution-based polymerizations.
View Article and Find Full Text PDFNatl Sci Rev
September 2025
College of Chemistry, Huazhong Agricultural University, Wuhan 430070, China.
The stress distribution in Li metal strongly affects the interfacial Li-ion diffusion, thereby influencing the morphology of plated Li and the performance of the battery. Here, we report a mechano-electrochemical coupling strategy that utilizes an arched structured carbon aerogel to achieve stable Li-plating/stripping electrochemistry. The arch-structured carbon aerogel can actively regulate stress distributions in response to the compressive stresses induced by Li deposition, generating the transition of stress from compressive on the convex surface to tensile on the concave surface, which can effectively promote the Li-migration kinetics and thus suppress the non-uniform deposition of Li.
View Article and Find Full Text PDFNanoscale Adv
July 2025
University of Kentucky, Department of Chemical and Materials Engineering 177 F.P. Anderson Tower Lexington Kentucky 40506-0046 USA
The crystallization behavior of ionic liquids (ILs) 1-butyl-3-methylimidazolium [BMIM] hexafluorophosphate [PF] and chloride [Cl] is investigated upon confinement in 2.3 or 8.2 nm diameter silica nanopore arrays, along with the effects of covalently modifying the pore walls with 1-(3-trimethoxysilylpropyl)3-methylimidazolium [TMS-MIM] groups.
View Article and Find Full Text PDFMed Phys
September 2025
Department of Radiology, Keio University School of Medicine, Tokyo, Japan.
Background: Understanding respiratory motions of liver and its surrogate organs is crucial for precise dose delivery in liver cancer radiotherapy. Although these motions have been studied for respiratory motion management in the supine posture, few studies have quantified them and evaluated their correlations in the upright posture.
Purpose: This study quantified the respiratory motions of liver and surrogate organs and evaluated the correlations between the liver motions and surrogate signals for respiratory motion monitoring in both the supine and upright postures.
SAR QSAR Environ Res
August 2025
Center for Medical Artificial Intelligence, Shandong University of Traditional Chinese Medicine, Qingdao, China.
Phosphorylation plays an important role in the activity of CDK2 and inhibitor binding, but the corresponding molecular mechanism is still insufficiently known. To address this gap, the current study innovatively integrates molecular dynamics (MD) simulations, deep learning (DL) techniques, and free energy landscape (FEL) analysis to systematically explore the action mechanisms of two inhibitors (SCH and CYC) when CDK2 is in a phosphorylated state and bound state of CyclinE. With the help of MD trajectory-based DL, key functional domains such as the loops L3 loop and L7 are successfully identified.
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