β-Thalassemia Trait Caused by a Defect: First Report of an Intragenic Deletion.

Hemoglobin

Department of Prenatal Diagnosis, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong Province, People's Republic of China.

Published: July 2025


Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Download full-text PDF

Source
http://dx.doi.org/10.1080/03630269.2025.2534709DOI Listing

Publication Analysis

Top Keywords

β-thalassemia trait
4
trait caused
4
caused defect
4
defect report
4
report intragenic
4
intragenic deletion
4
β-thalassemia
1
caused
1
defect
1
report
1

Similar Publications

Crop growth rate is a critical physiological trait for forage and bioenergy crops like sorghum [Sorghum bicolor (L.) Moench], influencing overall crop productivity, particularly in photoperiod-sensitive (PS) types. Crop growth rate studies focus on either a physiological approach utilizing a few genotypes to analyze biomass accumulation or a genetic approach characterizing easily scorable proxy traits in larger populations.

View Article and Find Full Text PDF

The adverse effects of Western diets (WD), high in both fat and simple sugars, which contribute to obesity and related disorders, have been extensively studied in laboratory rodents, but not in non-laboratory animals, which limits the scope of conclusions. Unlike laboratory mice or rats, non-laboratory rodents that reduce body mass for winter do not become obese when fed a high-fat diet. However, it is not known whether these rodents are also resistant to the adverse effects of WD.

View Article and Find Full Text PDF

CRISPR technologies are rapidly transforming agriculture by enabling precise and programmable modifications across a wide range of organisms. This review provides an overview of CRISPR applications in crops, livestock, aquaculture, and microbial systems, highlighting key advances in sustainable agriculture. In crops, CRISPR has accelerated the improvement of traits such as drought tolerance, nutrient efficiency, and pathogen resistance.

View Article and Find Full Text PDF

The Epigenetic Regulation of Agronomic Traits and Environmental Adaptability in Brassicas.

Plant Cell Environ

September 2025

State Key Laboratory of North China Crop Improvement and Regulation, Key Laboratory of Vegetable Germplasm Innovation and Utilization of Hebei, Ministry of Education of China-Hebei Province Joint Innovation Center for Efficient Green Vegetable Industry, International Joint R & D Center of Hebei Prov

As essential sources of vegetables, oilseeds, and forage, Brassica crops exhibit complex epigenetic regulation mechanisms involving histone modifications, DNA modifications, RNA modifications, noncoding RNAs, and chromatin remodelling. The agronomic traits and environmental adaptability of crops are regulated by both genetic and epigenetic mechanisms, while epigenetic variation can affect plant phenotypes without changing gene sequences. Furthermore, the impact of epigenetic modifications on plant phenotype has accelerated the crop breeding process.

View Article and Find Full Text PDF