Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Introduction: Lichen planus (LP) is a distinct clinical entity that commonly affects the skin, hair, nails, and mucous membranes. Multiple clinical variants of LP with varying morphologies have been documented. This study aimed to analyze the clinical, epidemiological, and dermoscopic features of different variants of cutaneous LP in the Indian population.
Methods: This prospective observational study was conducted at a tertiary care hospital from January 2021 to August 2022. A total of 50 patients with a confirmed diagnosis of cutaneous LP were included. Demographic details, including age, disease duration, symptoms, and family history, were recorded.
Results: Among the 50 patients, 30 (60%) were female and 20 (40%) male, with an age range of 8-65 years (mean age: 37 ± 14 years). Classical LP was the most common variant observed (26 cases, 52%), followed by lichen planus hypertrophicus (LPH) in eight cases (16%) and eruptive LP in six cases (12%). Wickham's striae (WS) was the most common dermoscopic finding in classical LP (observed in 23 cases, 88.5%), but was absent in LPH, actinic LP, and lichen planus pigmentosus (LPP). The most frequent pigmentation patterns in classical LP were diffuse dots and diffuse globules, seen in three cases (11.5%). Pigmentation patterns were more variable in LPH and actinic LP. The background color was pink in classical and eruptive LP, and brownish in LPH, actinic LP, and LPP. It showed mixed shades in annular atrophic LP. No significant differences in demographic parameters were noted among the different variants.
Conclusion: WS was the most consistent dermoscopic feature in cases of classical cutaneous LP and can assist physicians in diagnosis. Detailed dermoscopic evaluation, combined with a comprehensive clinical history, is essential for diagnosing classical and atypical LP variants and differentiating them from clinically similar conditions. This approach offers important clues regarding the underlying histopathology.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12261969 | PMC |
| http://dx.doi.org/10.7759/cureus.86051 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
COMPARING THE EFFICACY OF VELSCOPE WITH VITAL STAINS IN THE DIAGNOSIS OF (COMMON)ORAL POTENTIALLY MALIGNANT DISORDERS AN OBSERVATIONAL STUDY.
J Stomatol Oral Maxillofac Surg
September 2025
Department of Oral Medicine and Radiology, Sree Sai Dental College, Srikakulam 532401, INDIA. Electronic address:
Objective: Oral potentially malignant disorders (OPMDs) are a diverse group of oral mucosal lesions that carry an increased risk of malignant transformation. Although biopsy is the gold standard for the diagnosis of these lesions, early detection is crucial, emphasizing the need to introduce more reliable non-invasive screening modalities. The aim of the study was to compare the efficacy of VELscope and vital tissue staining techniques as screening tools in the detection of early dysplastic changes in OPMDS, such as oral leukoplakia (OL), oral lichen planus (OLP) & oral submucous fibrosis (OSMF) with histopathological confirmation.
View Article and Find Full Text PDFAre the dermatological cut-off values of commercially available ELISAs for BP180-NC16A appropriate when applied for diagnosis of oral mucous membrane pemphigoid?. Results of a preliminary study.
Minerva Dent Oral Sci
September 2025
Division of Dermatology Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna Italy.
Background: Enzyme-linked immunosorbent assay (ELISA) kits for BP180-NC16A use different cutoff levels established for cutaneous bullous pemphigoid (BP). However, in oral mucous membrane pemphigoid (OMMP), circulating antibodies are reported to be less readily detectable than cutaneous BP and there is little evidence that these cut-off levels are suitable for OMMP. This study was performed to explore whether the available cutoff values of anti-BP180-NC16A ELISA used for cutaneous BP are equally effective when applied to OMMP or should benefit from an optimized cut-off value.
View Article and Find Full Text PDFCausal relationship between dietary factors and oral mucosal lesions: Two-sample Mendelian randomization analysis.
Medicine (Baltimore)
September 2025
Department of Stomatology, Taikang Tongji (Wuhan) Hospital, Wuhan, Hubei Province, P.R. China.
Previous studies have suggested potential associations between some dietary factors and oral mucosal lesions (OMLs), however, existing research could be biased due to limited sample size and unaccounted confounding factors. This study aimed to explore the causal relationships between 13 common dietary factors and 3 OMLs using 2-sample Mendelian randomization (MR) analysis. Data for the MR analysis were extracted from publicly available genome-wide association study statistics.
View Article and Find Full Text PDFCutaneous reaction to cancer treatment: Atezolizumab-induced lichen planus pemphigoides.
JAAD Case Rep
September 2025
Department of Dermatology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas.
Asynchronous Teledermatology Reduces Wait Times and Maintains High Adherence to Standard Care for Lichen Planus: A Retrospective Study.
Telemed Rep
July 2025
Department of Dermatology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Background: Lichen planus (LP) is a chronic inflammatory dermatosis with limited teledermatology data guiding its management.
Objective: To assess whether asynchronous teledermatology provides timely, guideline-adherent LP care comparable to in-person visits.
Methods: A retrospective study of 102 LP patients seen via asynchronous teledermatology ( = 45) or in-person ( = 57) from 2020 to 2024.