98%
921
2 minutes
20
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.dld.2025.06.010 | DOI Listing |
Eur Heart J Open
July 2025
Amsterdam UMC Location University of Amsterdam, Department of Experimental Vascular Medicine, Amsterdam Cardiovascular Sciences, Meibergdreef 9, 1105AZ Amsterdam, Netherlands.
Aims: Calcific aortic valve disease is the most common valvular heart disease characterized by an inflammatory response in the leaflets followed by fibro-calcific remodelling of valvular interstitial cells (VICs). Lipoprotein(a) [Lp(a)] is a well-recognized risk factor for CAVD, however the role of metabolism in driving Lp(a)-induced inflammation remains largely elusive. Therefore, we aim to investigate the role of Lp(a) in driving inflammatory and metabolic changes in VICs and examine how alterations in cellular metabolism can alter their inflammatory phenotype.
View Article and Find Full Text PDFCirc Res
August 2025
Division of Critical Care, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN.
Eur Respir J
August 2025
Pulmonary Vascular Diseases Unit, Royal Papworth Hospital, Cambridge, UK.
https://bit.ly/4eetchF
View Article and Find Full Text PDFMalays Orthop J
July 2025
Emergency Department, Esenyurt Necmi Kadioglu State Hospital, Istanbul, Turkey.
Diabetes Care
September 2025
Veterans Administration Tennessee Valley VA Health Care System Geriatric Research Education Clinical Center (GRECC), Nashville, TN.