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Carriers can remarkably reduce transportation costs and emissions when they collaborate, for example through a platform. Such gains, however, have only been investigated for relatively small problem instances with low numbers of carriers. We develop auction-based methods for large-scale dynamic collaborative pickup and delivery problems, combining techniques of multi-agent systems and combinatorial auctions. We evaluate our approach in terms of both solution quality and possibilities of strategic behaviour using a real-world data set of over 12,000 orders. Hence, this study is (to the best of our knowledge) the first to assess the benefits of large-scale carrier cooperation and to propose an approach for it. First, we use iterative single-order auctions to investigate possible collaboration gains for increasing numbers of carriers. Our results show that travel costs can be reduced by up to 77% when 1000 carriers collaborate, largely increasing the gains that were previously observed in smaller-scale collaboration. We also ensure that individual rationality is guaranteed in each auction. Next, we compare this approach of multiple local auctions with an established central combinatorial auction mechanism and observe that the proposed approach performs better on large-scale instances. Furthermore, to improve solution quality, we integrate the two approaches by allowing small bundle auctions in the multi-agent system. We analyze the circumstances under which bundling is beneficial in a large-scale decentralized system and demonstrate that travel cost gains of up to 13% can be obtained for 1000 carriers. Finally, we investigate whether the system is vulnerable to cheating: we show that misrepresentation of true values by individual participants sometimes can benefit them at the cost of the collective. Although such strategic behaviour is not straightforward, we also discuss different means to prevent it.
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http://dx.doi.org/10.1007/s10479-021-04504-3 | DOI Listing |
Sci Justice
September 2025
Department of Chemistry and Forensic Science, Eastern Kentucky University, 521 Lancaster Avenue, Richmond, KY 40475, United States. Electronic address:
Traditionally, when processing DNA samples, a multiple-step procedure is followed; after a sample has been collected, DNA is then extracted and quantified before a profile is generated. During the process, valuable DNA can be lost and/or consumed. When processing reference samples, where DNA is usually in abundance, DNA loss may not be a concern for the analysts.
View Article and Find Full Text PDFVet Microbiol
September 2025
College of Animal Science and Technology/Laboratory of Functional Microbiology and Animal Health, Henan University of Science and Technology, Luoyang 471023, PR China; Luoyang Key Laboratory of Live Carrier Biomaterial and Animal Disease Prevention and Control, Henan University of Science and Techno
Bovine Viral Diarrhea Virus (BVDV) is a major pathogen associated with calf diarrhea and reproductive disorders in cattle. This study evaluated the immune-protective potential of a subunit vaccine based on the capsid C protein of the BVDV HNL-1 strain. In mice model, the C protein subunit vaccine exhibits a favorable safety and elicits robust immune-protective efficacy comparable to commercial inactivated vaccines.
View Article and Find Full Text PDFSports Med Open
September 2025
Division of Physiological Sciences, Department of Human Biology, Faculty of Health Sciences, University of Cape Town, Newlands, Cape Town, 7725, South Africa.
Background: In tackle-collision sports, the tackle has the highest incidence, severity, and burden of injury. Head injuries and concussions during the tackle are a major concern within tackle-collision sports. To reduce concussion and head impact risk, evaluating optimal tackle techniques to inform tackle-related prevention strategies has been recommended.
View Article and Find Full Text PDFJDS Commun
September 2025
Livestock Improvement Corporation Ltd., Newstead, Hamilton 3240, New Zealand.
SLICK1 is an allelic variant of the prolactin receptor () that is found in Senepol beef cattle. The presence of a single copy of this allele produces a short hair coat and confers heat tolerance. We aimed to determine the effect of 2 copies of this allele on milking performance of dairy cattle.
View Article and Find Full Text PDFSmall
September 2025
Key Laboratory of Luminescence Analysis and Molecular Sensing, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, P. R. China.
Perovskites have a large number of intrinsic defects and interface defects, which often lead to non-radiative recombination, and thus affect the efficiency of perovskite solar cells (PSCs). Introducing appropriate passivators between the perovskite layer and the transport layer for defect modification is crucial for improving the performance of PSCs. Herein, two positional isomers, 1-naphthylmethylammonium iodide (NMAI) and 2-naphthylmethylammonium iodide (NYAI) are designed.
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