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This case report presents a unique instance of condyloma acuminata in a one-year-old child, which adds to the scientific literature by highlighting the potential for non-sexual transmission in pediatric patients. The child exhibited a rapidly enlarging, skin-colored lump around the anus, initially a small bump that soon resembled a cauliflower. Acetowhite testing was positive, and histopathological examination revealed hyperkeratosis, acanthosis, and papillomatosis, leading to the diagnosis of condyloma acuminata. The main therapeutic intervention involved the application of 90% trichloroacetic acid (TCA), resulting in complete lesion resolution after two treatments, with no recurrence observed over a six-month follow-up period. This case emphasizes the urgent need for special attention to sexually transmitted infections (STIs) in children, considering the potential link to sexual violence. It highlights the critical, holistic role of venereology specialists, not only in providing effective and safe curative treatments but also in actively preventing further transmission and supporting vulnerable patients like children.
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http://dx.doi.org/10.11604/pamj.2025.50.101.45681 | DOI Listing |
Int J Infect Dis
August 2025
Peking University, Beijing, China.
Objectives: Anogenital warts (AGW) are a common manifestation of human papillomavirus (HPV) infection. As HPV vaccination programs expand, updated data are needed to assess the ongoing global AGW burden. This systematic review examined AGW epidemiology, clinical impact, and economic burden, analyzing 187 studies from 49 countries by income level, sex, and age.
View Article and Find Full Text PDFInt J STD AIDS
August 2025
Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
BackgroundNew guidelines recommend anal cancer screening for priority populations with increased likelihoods of anal cancer including people with a history of HIV, gynecologic cancers, condyloma acuminata, and solid organ transplantation. However, little is known about U.S.
View Article and Find Full Text PDFInt J STD AIDS
August 2025
Department of Dermatology, Civil Hospital, Nabha, India.
Topical imiquimod is widely used for the treatment of external anogenital warts due to its potent immunomodulatory effects. Although local skin reactions are common, systemic side effects are rare and under-recognized. We describe the case of a 23-year-old male who developed recurrent, cytokine-mediated systemic symptoms-including fever, myalgias, and malaise-within hours of each application of imiquimod 5% cream to condylomata acuminata on the glans penis and inner prepuce.
View Article and Find Full Text PDFMed Anthropol
September 2025
Department of Community Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, Canada.
Human papillomavirus (HPV)-related anal infection is high among African gay, bisexual, and other men who have sex with men (MSM). In Kenya, queer men living with HPV-related anal warts often avoid health facilities, fearing homophobic retaliation from providers. In this paper, we present data collected over 24 months of ethnographic research, foregrounding the therapeutic trajectories of 35 men with advanced cases of anal warts requiring surgical intervention.
View Article and Find Full Text PDFSurg Innov
July 2025
Gastrointestinal Surgery, San Raffaele Scientific Institute, Milan, Italy.
AimAnal Intraepithelial Neoplasia has been a hot topic in colorectal surgery and many Scientific Societies have produced guidelines for their diagnosis and treatment. This study aims to appraise the quality of the existing guidelines in this field.MethodsA systematic review of the Literature was conducted in PubMed, EMBASE and Scholar Google databases.
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