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Background: Mandibular reconstruction is a critical procedure in the management of defects caused by trauma, tumors, or congenital anomalies. Traditional methods often face challenges such as poor fit, extended surgery time, and postoperative complications. The advent of 3D printing technology allows for the precise fabrication of titanium implants tailored to individual anatomy. This study evaluates the clinical outcomes of using 3D-printed titanium implants in mandibular reconstruction.
Materials And Methods: This prospective study involved 30 patients (mean age: 45 ± 12 years) with mandibular defects requiring reconstruction. Customized 3D-printed titanium implants were designed using preoperative CT scans and fabricated using laser powder bed fusion technology. Surgical procedures included implant placement combined with soft tissue grafts where necessary. Follow-ups were conducted at 1, 3, 6, and 12 months postoperatively to assess implant stability, functional outcomes (mastication and speech), and aesthetic satisfaction. Data were analyzed using descriptive statistics and paired -tests for functional improvement.
Results: All patients successfully underwent implantation without intraoperative complications. At 12 months, the implant survival rate was 96.7%. Functional assessment showed a significant improvement in chewing efficiency (mean increase: 40%, < 0.001) and speech clarity (mean increase: 30%, < 0.001). Patient satisfaction regarding aesthetics was high, with 85% rating outcomes as excellent. Postoperative complications included mild infection in two patients (6.7%) and implant loosening in one patient (3.3%), all managed successfully.
Conclusion: 3D-printed titanium implants demonstrated excellent clinical efficacy and safety in mandibular reconstruction, offering significant functional and aesthetic benefits. The technology holds promise for personalized care in maxillofacial surgery, though long-term studies are needed to confirm these findings.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12244566 | PMC |
http://dx.doi.org/10.4103/jpbs.jpbs_1816_24 | DOI Listing |
Adv Healthc Mater
September 2025
Krembil Research Institute, Toronto Western Hospital, University Health Network, Toronto, ON, M5T 0S8, Canada.
Accurate brain signal recording and precise electrode placement are critical for the success of neuromodulation therapies such as deep brain stimulation (DBS). Addressing these challenges requires deep brain electrodes that provide high-quality, stable recordings while remaining compatible with high-resolution medical imaging modalities like magnetic resonance imaging (MRI). Moreover, such electrodes shall be cost-effective, easy to manufacture, and patient-compatible.
View Article and Find Full Text PDFJ Prosthodont
September 2025
Department of Reconstructive Dentistry and Gerodontology, School of Dental Medicine, University of Bern, Bern, Switzerland.
Purpose: This study aimed to evaluate the inherent and after cyclic loading fracture strength of implant-supported cantilevered fixed prostheses fabricated from recently introduced additively manufactured (AM) and subtractively manufactured (SM) materials, considering variations in prosthesis height.
Materials And Methods: Three cylinder-shaped master files (20 mm long and 11 mm wide) with varying heights (7, 11, and 15 mm) and a titanium-base (Ti-base) abutment space were designed. These designs were used to fabricate a total of 144 specimens with two AM resins indicated for definitive use (Crowntec; AM-CT and Flexcera Smile Ultra+; AM-FS), one high-impact polymer composite (breCAM.
Clin Cosmet Investig Dent
August 2025
Department of Periodontology, Faculty of Dentistry, Universitas Padjadjaran, Sumedang, West Java, Indonesia.
Titanium is widely used for dental implant abutments due to its mechanical strength, biocompatibility, and corrosion resistance; however, its gray coloration can compromise esthetic outcomes, particularly in patients with thin or translucent gingival biotypes. Anodization, a surface modification technique altering the titanium oxide layer, has been proposed to improve soft tissue aesthetics by producing abutments with warmer tones (eg, pink or gold) that harmonize with the surrounding gingiva. This systematic review aimed to evaluate the clinical and aesthetic outcomes of anodized titanium abutments compared to non-anodized titanium and other materials, with a focus on peri-implant soft tissue health and visual integration.
View Article and Find Full Text PDFCureus
August 2025
Dental and Oral Medical Center, Kurume University School of Medicine, Kurume, JPN.
Functional reconstruction of large mandibular defects, especially in young patients, presents a significant clinical challenge. The ideal approach should not only restore skeletal contour but also address nerve deficits and facilitate final occlusal rehabilitation, all while minimizing morbidity. This report describes a comprehensive, multi-staged strategy for such a case.
View Article and Find Full Text PDFJ Orthop Translat
November 2025
AO Research Institute Davos, Davos, Switzerland.
Background/objective: Plate failure, including bending, is a critical issue in orthopedic fracture fixation, with clinical failure rates of 3.5%-19%, burdening patients and healthcare systems. Preclinical ovine models have observed similar plate bending due to overloading.
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