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Chicken is a primary source of food worldwide. Ensuring food safety and preserving public health is crucial, and chicken meat inspection plays a critical role in achieving this goal. The transfer of pathogenic bacteria from animal intestines to carcasses during processing, and subsequently from meat products to consumers, is a significant contributor to the growing incidence of resistance and foodborne illnesses. This study aimed to examine the antimicrobial resistance of present in chicken liver. Fifty samples of chicken liver were collected from various areas of Peshawar and screened for resistant . The bacteria were tested against different antibiotics, including Moxifloxacin, Vancomycin, Linezolid, Gentamycin, and Clindamycin. Gentamycin demonstrated the highest susceptibility against the maximum bacterial isolates, with 100% susceptibility as its P-value was less than 0.05. Other antibiotics showed effective results. Linezolid was 66.7% susceptible. Both vancomycin and Clindamycin were 41.6% susceptible, while Moxifloxacin was 33.3% susceptible. This study concludes that isolated from chicken liver has the potential to cause multiple diseases. The screened pathogens were not only resistant to single antibiotics but also showed resistance to multiple antibiotics. The cut-off values of the isolates were two folds higher than those reported in CLSI 2023. The findings highlight the need for effective measures to control the spread of antimicrobial-resistant bacteria and to ensure food safety.
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http://dx.doi.org/10.1007/s12088-024-01401-8 | DOI Listing |
Vet Med Sci
September 2025
Department of Pharmacology and Toxicology, Faculty of Veterinary, Animal and Biomedical Sciences, Sylhet Agricultural University, Sylhet, Bangladesh.
The emergence of antimicrobial resistance (AMR) Escherichia coli in poultry farming is a growing global public health concern, particularly in Bangladesh, where the use of antibiotics remains largely unregulated. This study aimed to determine the prevalence and AMR patterns of E. coli isolated from broiler chickens in Sylhet district of Bangladesh and to investigate the network of coexisting resistance traits among the isolates.
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August 2025
Guangdong Key Laboratory for Veterinary Drug Development and Safety Evaluation, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Amphenmulin is a novel pleuromutilin derivative with proven excellent antibacterial activity. To investigate its metabolism in animals, ultra-high-performance liquid chromatography coupled with quadrupole/time-of-flight mass spectrometry (UHPLC-Q-TOF-MS/MS) was employed to analyze and identify metabolites in rats and chickens and using human, rat, pig, chicken and beagle dog liver microsomes. We identified 18 metabolites from liver microsomes and 24 and 17 metabolites for rats and chickens, respectively.
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September 2025
College of Biology and Environmental Engineering, Zhejiang Shuren University, Hangzhou 310023, China.
This study investigated the protective effects of Bacillus subtilis fmbj (BS) in alleviating hepatic immune stress and redox imbalance induced by lipopolysaccharide (LPS) in broilers. A total of 240 chickens were randomly assigned to three groups, each consisting of ten replicates with eight birds per replicate. Birds in the LPS and BSLPS groups received intraperitoneal injections of LPS (1 mg/kg body weight), whereas the CON group was administered an equivalent volume of 0.
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August 2025
Centre for Genetic Improvement of Livestock, Department of Animal Biosciences, University of Guelph, Guelph, ON, Canada; Centre for Nutrition Modelling, Department of Animal Biosciences, University of Guelph, Guelph, ON, Canada; Department of Animal and Veterinary Sciences, Aarhus University, Bliche
Late-stage mortality is a significant challenge for the poultry industry, leading to substantial economic losses, concerns about animal welfare, and operational sustainability. Heart-related conditions, including ascites syndrome, pulmonary hypertension syndrome, hypertrophic cardiomyopathy, and sudden death syndrome, contribute significantly to this issue. The increasing prevalence of these conditions is potentially linked to intense selection pressure aimed at maximizing meat yield, particularly breast meat.
View Article and Find Full Text PDFBiology (Basel)
July 2025
Tropical Crops Genetic Resources Institute, Chinese Academy of Tropical Agricultural Sciences, Danzhou 571700, China.
Marek's disease (MD), induced by the highly contagious Marek's disease virus (MDV), remains a significant challenge to global poultry health despite extensive vaccination efforts. This study employed integrated transcriptomic and metabolomic analyses to investigate liver responses in naturally MDV-infected Wenchang chickens during late infection stages. RNA sequencing identified 959 differentially expressed genes (DEGs) between the infected and uninfected groups.
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