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This paper presents the optimal planning of multi-area, multi-service, and multi-tier edge-cloud environments. The goal is to evaluate the regional deployment of the compute continuum, i.e., the type and number of processing devices, their pairing with a specific tier and task among different areas subject to processing, rate, and latency requirements. Different offline compute continuum planning approaches are investigated and detailed analysis related to various design choices is depicted. We study one scheme using all tasks at once and two others using smaller task batches. The latter both iterative schemes finish once all task groups have been traversed. Group-based approaches are presented as dealing with potentially excessive execution times for real-world sized problems. Solutions are provided for continuum planning using both direct complex and simpler, faster methods. Results show that processing all tasks simultaneously yields better performance but requires longer execution, while medium-sized batches achieve good performance faster. Thus, the batch-oriented schemes are capable of handling larger problem sizes. Moreover, the task selection strategy in group-based schemes influences the performance. A more detailed analysis is performed in the latter case, and different clustering methods are also considered. Based on our simulations, random selection of tasks in group-based approaches achieves better performance in most cases.
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http://dx.doi.org/10.3390/s25133949 | DOI Listing |
Herz
September 2025
Department of Cardiology, Heart Center Leipzig, University of Leipzig, Strümpellstraße 39, 04289, Leipzig, Deutschland.
Since the earliest studies on transcatheter aortic valve implantation (TAVI), the heart team concept has been an integral component of treatment planning for patients with aortic valve stenosis (AS). The primary objective is to ensure patient-specific, guideline-based treatment through the structured involvement of all relevant medical disciplines. The TAVI heart team is strongly recommended with a class I indication in both European and US clinical guidelines.
View Article and Find Full Text PDFCureus
July 2025
Department of Prosthodontics, Sardar Patel Post Graduate Institute of Dental and Medical Sciences, Lucknow, IND.
Craniofacial rehabilitation demands a multidisciplinary approach where prosthodontists play a pivotal yet often underutilized role in the continuum of care. Traditionally, prosthetic rehabilitation is considered a postsurgical step, leading to delays in functional restoration and compromised outcomes. This editorial emphasizes the need to redefine prosthodontics as an integral component of craniofacial surgical planning, from the operating room to the dental chair.
View Article and Find Full Text PDFInt J Integr Care
August 2025
School of Population Health, University of New South Wales, AU.
Introduction: Integrated care has been adopted as a guiding principle to reduce fragmentation and to make health systems more person-centred. Successful integration requires care services and processes that include primary care, specialist care, and acute services. To promote learning and development in the field, flexible and adaptable empirically derived frameworks for different contexts, conditions and settings are required.
View Article and Find Full Text PDFMed Klin Intensivmed Notfmed
August 2025
Interdepartmental Division of Critical Care Medicine, Mount Sinai Hospital, Sinai Health System, University of Toronto, Toronto, Canada.
A thorough understanding of oncological disease status is crucial for managing critically ill patients with cancer. The cancer trajectory predisposes patients to the type of critical illness they could develop and shapes the likelihood of reversibility and the chance for meaningful recovery, including continuation of therapy. This review outlines how disease status-whether new diagnosis, remission, stable disease, or progression-directly impacts differential diagnosis and treatment goals in the intensive care unit (ICU).
View Article and Find Full Text PDFPLoS One
August 2025
School of International Development and Global Studies, University of Ottawa, Ottawa, Ontario, Canada.
Introduction: In Ethiopia, Maternal, Newborn, and Child Health (MNCH) outcomes have been improving, however, the current level of Maternal and under-five children mortality remains the highest in the world. Despite the rhetoric around the significance of multi-stakeholder engagement as a buzzword in development theories and polices to improve health and other development outcomes, there is limited evidence on how multi-stakeholders intersect and mutually reinforce each other toward the coproduction of improved MNCH outcomes and a resilient community health system. The aim of this manuscript is to examine barriers to and facilitators of coproduction in the context of multi-stakeholder engagement to optimize MNCH outcomes and a resilient community health system in rural Ethiopia.
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