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Background/introduction: The disease prediction process plays a crucial part in a person's life "to lead a healthy life." The sudden spread of the data mining approach has generated the disease forecasting system. Secure transfer of medical data and effective storage is the major difficulty faced by recent healthcare management. Moreover, there is significant attention towards privacy preservation, especially for medical information, which is highly sensitive. For disease prediction, several prevailing privacy preservation approaches have been developed. "Moreover, although the disease prediction system is auspicious, its complexity may limit practical use, including information security and prediction efficiency."
Methods: Multimodal user authentication is performed by a Multi-scale Cross Attention-based Residual Network (MCARNet) to prevent unauthorized access to the healthcare system. Images and signals are converted into 2D images for performing the encryption using the Optimal Rossler Hyper Chaotic Encryption (ORHCE). The decrypted images are given to the same MCARNet for predicting the disease.
Results: The precision of the developed model was enhanced by 7.3% of DNN, 12.3% of RNN, 3.6% of LSTM, and 4.3% of GRU when taking the k fold value as 5.
Conclusion: The multimodal user authentication and disease detection using the proposed heuristic-based hybrid deep learning model enhanced its authentication and detection performance.
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http://dx.doi.org/10.1016/j.cmpb.2025.108928 | DOI Listing |
Haematologica
September 2025
Division of Hematopathology, Department of Pathology and Laboratory Medicine, Weill Cornell Medicine/NewYork-Presbyterian Hospital, New York, NY; Multiparametric In Situ Imaging (MISI) Laboratory, Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York.
Not available.
View Article and Find Full Text PDFAmyotroph Lateral Scler Frontotemporal Degener
September 2025
Brain and Nerve Research Centre, Concord Clinical School, University of Sydney, Concord Hospital, Sydney, Australia.
: Neck flexion (NF) weakness is a frequently observed clinical feature in amyotrophic lateral sclerosis (ALS), particularly in advanced disease. The aim of the present study was to assess whether NF weakness could be a clinical biomarker for development of respiratory dysfunction. : Sixty-two ALS patients were prospectively recruited at Brain and Nerve Research Center.
View Article and Find Full Text PDFArthritis Care Res (Hoboken)
September 2025
Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Background: Interstitial lung disease (ILD) is a significant cause of morbidity and mortality in systemic sclerosis (SSc), particularly among Black patients. Pulmonary function tests (PFTs) are critical to screen for and monitor SSc-ILD. We examined whether race-specific and race-neutral PFT reference equations impact classification of restrictive lung disease (RLD) severity in Black and White patients with SSc.
View Article and Find Full Text PDFCirc Genom Precis Med
September 2025
Division of Cardiology, Emory University School of Medicine, Atlanta, GA. (A.K.Y., A.C.R., L.S.S., A.A.Q., Y.V.S.).
Background: Cardio-kidney-metabolic (CKM) disease represents a significant public health challenge. While proteomics-based risk scores (ProtRS) enhance cardiovascular risk prediction, their utility in improving risk prediction for a composite CKM outcome beyond traditional risk factors remains unknown.
Methods: We analyzed 23 815 UK Biobank participants without baseline CKM disease, defined by -Tenth Revision codes as cardiovascular disease (coronary artery disease, heart failure, stroke, peripheral arterial disease, atrial fibrillation/flutter), kidney disease (chronic kidney disease or end-stage renal disease), or metabolic disease (type 2 diabetes or obesity).
Rev Med Liege
September 2025
Service de Néphrologie, CHU Liège, Belgique.
ANCA-associated vasculitis, such as granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA), are rare systemic diseases causing necrotizing inflammation of small blood vessels. Renal involvement is common, leading to acute kidney injury with hematuria and proteinuria. Diagnosis is based on serological tests (PR3-ANCA, MPO-ANCA) and renal histology via biopsy, which helps assess the extent of lesions.
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