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Introduction: This review and meta-analysis aimed to examine the effects of virtual reality (VR) therapy on lymphedema and disability management in post-mastectomy breast cancer patients, following PRISMA protocol.
Methods: Databases were extensively searched, including Wiley Online Library, ProQuest, MEDLINE, CINAHL, Google Scholar, Science Direct, and SAGE Journals, covering studies from January 2016 to August 2024. This review was reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
Results: Nine studies met the inclusion criteria. The findings indicate VR therapy effectively reduces post-mastectomy lymphedema and aids upper limb disability rehabilitation, with sessions lasting 10-50 min. The meta-analysis statistics showed a significant decrease in disability, measured by the disability of the arm, shoulder, and hand (DASH) scale, with an effect size of -0.931 ( score = -2.713, = 0.007) and a 95% confidence interval of -1.604 to -0.259.
Conclusions: These results strongly support VR's efficacy in managing lymphedema and disability, recommending its integration into routine care at oncology centers and hospitals. This article explains compelling evidence that VR is effective in helping patients with lymphedema manage their disabilities. Rehabilitation programs using VR after mastectomy should be incorporated into the daily care in oncology centers and hospitals. Further interventional studies are needed to strengthen evidence and refine VRs clinical application.
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http://dx.doi.org/10.1159/000546605 | DOI Listing |
PLoS Negl Trop Dis
September 2025
Unit of Clinical and Molecular Medicine, ICMR-Vector Control Research Centre (VCRC), Indira Nagar, Puducherry, India.
Background: Filarial lymphedema, caused by lymphatic filariasis, is characterized by chronic swelling and recurrent skin infections. Acute adenolymphangitis (ADL) episodes significantly exacerbate morbidity. Diabetes mellitus (DM) increases susceptibility to infections; however, the relationship between diabetes and ADL frequency and severity in filarial lymphedema patients remains unclear.
View Article and Find Full Text PDFDisabil Rehabil
September 2025
Department of Rehabilitation Sciences and Physiotherapy, University of Leuven, Leuven, Belgium.
Purpose: This study aims to cross-culturally validate the Dutch version of the Lymphedema Symptom Intensity and Distress Survey-Head and Neck version 2.0 (LSIDS-H&N v2.0).
View Article and Find Full Text PDFMedicina (Kaunas)
July 2025
Department of Medicine, Surgery and Dentistry, University of Salerno, 84081 Baronissi, Italy.
Breast cancer therapy is a common cause of lymphedema. The accumulation of protein-rich fluid in the affected extremity leads to a progressive path-swelling, inflammation, and fibrosis-namely, irreversible changes. A scientific literature analysis was performed on PubMed/Medline, Scopus, Web of Science (WoS), the Cochrane Central Register of Controlled Trials (CENTRAL), and the Physiotherapy Evidence Database (PEDro) from inception until 30 June 2024.
View Article and Find Full Text PDFAm J Transl Res
July 2025
Department of Breast Surgery, Hainan General Hospital Haikou 570311, Hainan, China.
Objective: To observe the influence of internet platform tracking management mode combined with progressive resistance training (PRT) on the rehabilitation of patients with breast cancer-related lymphedema (BCRL).
Methods: A total of 100 patients with BCRL admitted to Hainan general hospital from January 2023 to March 2024 were selected. After the shedding cases were excluded, they were divided into group A (n=47) where PRT + out-of-hospital follow-up were given, and group B (n=48) where PRT + Internet platform tracking management mode was given.
PLoS Negl Trop Dis
August 2025
Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Background: Neglected tropical diseases (NTDs) such as lymphatic filariasis (LF) are a significant concern in developing countries like Bangladesh. Understanding the health and social needs of individuals with LF is essential for improving their healthcare-seeking experiences and advancing the health system's capacity. Therefore, this qualitative study aimed to explore the social and care-seeking experiences of persons with LF in Bangladesh.
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