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Introduction: Cardiometabolic pregnancy complications increase future cardiometabolic disease risk. Accurate risk perception plays a central role in adopting risk-reducing lifestyle and health-related behaviors, such as healthy eating, physical activity, and weight management. This review aimed to explore high-risk pregnant and postpartum women's perception of their risk of developing cardiometabolic pregnancy complications or future cardiometabolic disease.
Methods: Systematic search identified quantitative and qualitative data exploring risk perception in women (pregnant/postpartum) at risk of or diagnosed with gestational diabetes mellitus (GDM), hypertensive disorders of pregnancy (HDP), intrauterine growth restriction (IUGR), and preterm birth (PTB). A convergent integrated mixed-methods synthesis was undertaken, with findings interpreted using the health belief and capability, opportunity, and motivation for behavior change models.
Results: Overall, 84 studies were included, with the majority in GDM (77.4%) and HDP (23.8%), with limited research in PTB (8.3%) and IUGR (6.0%). Women had low-moderate knowledge of pregnancy complications as risk factors for future cardiometabolic disease and low-moderate perceived susceptibility to potential pregnancy complications and future cardiometabolic disease. Self-perceived barriers, facilitators, cues to action, self-efficacy, and self-optimism impacted engagement with lifestyle and screening measures. The highest risk perception for future type 2 diabetes or cardiovascular disease was among women who had previously experienced GDM or HDP, respectively.
Conclusion: Designing interventions to optimize women's risk perception will support informed decision-making and empower women to make lifestyle changes to reduce future cardiometabolic risk.
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http://dx.doi.org/10.1111/obr.13967 | DOI Listing |
J Proteome Res
September 2025
Department of Neurology, West China Hospital, Sichuan University, Chengdu 610207, China.
Myasthenia gravis (MG) presents significant health and economic challenges. To identify novel biomarkers, we analyzed proteomic data from 52,704 UK Biobank individuals, focusing on 1463 baseline proteins with follow-up >10 years. Baseline and potential MG cases were 1:5 matched to controls by using propensity score matching.
View Article and Find Full Text PDFSleep Adv
July 2025
Lindner Center of HOPE Research Institute, Mason, OH, United States.
Study Objectives: Dim light melatonin onset (DLMO) is the best-established marker of central circadian phase and may contribute to unraveling the role of the circadian system in obesity. This study evaluated DLMO among individuals with obesity using a home-based assessment and explored its clinical correlates and procedural variations.
Method: Fifty-eight women (mean [SD] age 40.
J Nutr
September 2025
School of Medicine and Allied Health Sciences, University of The Gambia, Banjul, The Gambia; Shandong Provincial Key Laboratory of Precision Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University & Shandong Academy of Medical Sciences, 440 Jiyan Road, Jinan, Shandong 250
Background: Red and processed meat consumption is extensively linked to chronic disease risk in observational studies, with robust meta-analyses demonstrating significant positive associations for colorectal, breast, endometrial, and lung cancers, type 2 diabetes (T2DM), cardiovascular disease (CVD), and all-cause mortality. Dose-response relationships indicate elevated risks even at moderate intakes. Moreover, processed meats consistently show stronger detrimental effects than unprocessed red meats.
View Article and Find Full Text PDFEur J Prev Cardiol
September 2025
Institute of Clinical Chemistry, University and University Hospital of Zurich, Zurich, Switzerland.
Aims: Bariatric surgery (BS) reduces obesity-associated systemic inflammation leading to multiple cardiovascular (CV) and metabolic benefits. Here, we tested whether measuring vaso-inflammatory cytokines, gut hormones, and circulating extracellular vesicles (EV) provide vaso-inflammatory-metabolic signatures that better correlate to CV-metabolic outcomes after BS, compared to a standard clinical assessment including body weight (BW) loss and traditional CV risk factors.
Methods: In 111 patients with severe obesity, conventional clinical-biochemical parameters and non-conventional vaso-inflammatory-metabolic markers were analyzed at baseline, after 1- (T12) and 3-years (T36) post-BS and were associated to post-surgical BW loss and improvement of patients' CV-metabolic profile.
J Nutr
September 2025
Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston,
Food is Medicine (FIM) initiatives are food-based nutrition interventions to prevent or manage chronic disease and improve overall health. It is increasingly embraced across healthcare systems, policy makers, and researchers as a promising strategy to address diet-related chronic diseases. Despite this enthusiasm, questions have been raised about whether FIM is overhyped given the still limited evidence.
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