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http://dx.doi.org/10.1093/ije/dyaf091 | DOI Listing |
Kidney360
September 2025
Department of Pediatrics, Division of Pediatric Nephrology, Baylor College of Medicine, Houston, TX, United States.
Background: Dialysis in neonates with ESKD is often associated with multiple comorbidities and the need for more intensified dialysis regimens. With recent advances in prenatal interventions and infant specific KRT, survival of neonates with ESKD has improved over the last decade. Little is known however about the impact on the health care system of improved survival in this population.
View Article and Find Full Text PDFAppl Biochem Biotechnol
September 2025
School of Biological Sciences, University of the Punjab, Quaid-E-Azam Campus, P.O. 54590, Lahore, Pakistan.
Recombinant DNA technology is widely used to produce industrially and pharmaceutically important proteins. In silico analysis, performed before executing wet lab experiments has been greatly helpful in this connection. A shift in protein analysis has been observed over the past decade, driven by advancements in bioinformatics databases, tools, software, and web servers.
View Article and Find Full Text PDFCNS Drugs
September 2025
Global Health Neurology Lab, Sydney, NSW, 2150, Australia.
Acute ischemic stroke (AIS) remains a leading cause of mortality and long-term disability globally, with survivors at high risk of recurrent stroke, cardiovascular events, and post-stroke dementia. Statins, while widely used for their lipid-lowering effects, also possess pleiotropic properties, including anti-inflammatory, endothelial-stabilizing, and neuroprotective actions, which may offer added benefit in AIS management. This article synthesizes emerging evidence on statins' dual mechanisms of action and evaluates their role in reducing recurrence, improving survival, and mitigating cognitive decline.
View Article and Find Full Text PDFJ Robot Surg
September 2025
Department of Research and Innovation, Medway NHS Foundation Trust, Gillingham, ME7 5NY, UK.
Robotic surgery has transformed the field of surgery, offering enhanced precision, minimal invasiveness, and improved patient outcomes. This narrative review explores the multifaceted aspects of robotic surgery, examining the challenges, recent advances, and future prospects for its integration into healthcare. Our comprehensive analysis of 48 studies reveals significant geographic disparities in robotic surgery research and implementation, with 68.
View Article and Find Full Text PDFTheor Appl Genet
September 2025
Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Gatersleben, Germany.
The German Federal Ex Situ Genebank for Agricultural and Horticultural Crops (IPK) harbours over 3000 pea plant genetic resources (PGRs), backed up by corresponding information across 16 key agronomic and economical traits. The unbalanced structure and inconsistent format of this historical data has precluded effective leverage of genebank accessions, despite the opportunities contained in its genetic diversity. Therefore, a three-step statistical approach founded in linear mixed models was implemented to enable a rigorous and targeted data curation.
View Article and Find Full Text PDF