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Hydronephrotic lower moiety of duplex systems: Observations using diuresis renography.
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- This study examines hydronephrosis in the lower part of duplex kidneys, using a technique called MAG-3 diuresis renography to assess its prevalence and behavior compared to single-system kidney obstructions.* -
- Researchers analyzed over 5000 diuresis renograms and identified 19 affected renal units in 18 patients, noting that many cases were diagnosed before birth and showed varied drainage patterns during follow-up.* -
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Evaluation of renal tubular function by multiparametric functional MRI in early diabetes.
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Purpose To evaluate the tubular function in an alloxan-induced type 1 diabetes mellitus (DM) rabbit model measured by renal oxygenation (R2*), oxygen extraction fraction (OEF), and renal blood flow (RBF) using blood oxygenation level dependent, asymmetric spin echo, and arterial spin labeling MRI. Methods Twenty-six rabbits were randomized into the 3-day DM group (n = 13) and the 7-day DM group (n = 13). We performed pairs of multiparametric MRIs (before and after furosemide injection) at baseline and 3/7 days post-DM, and scored pathological kidney injury.
View Article and Find Full Text PDFDecreased percent change in renal pelvis diameter on diuretic functional magnetic resonance urography following administration of furosemide may help characterize unilateral uretero-pelvic junction obstruction.
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Department of Radiology, Emory University and Children's Healthcare of Atlanta, Atlanta, GA, USA. Electronic address:
Background: A well-established definition of obstruction in the setting of congenital hydronephrosis is lacking. Multiple imaging modalities and radiographic characteristics or parameters have been described to help confirm the diagnosis of ureteropelvic junction obstruction (UPJO). We sought to evaluate the change in anterior-posterior renal pelvic diameter (APRPD) following furosemide administration in patients with unilateral hydronephrosis and confirmed UPJO on functional magnetic resonance urography (fMRU) who underwent pyeloplasty.
View Article and Find Full Text PDFInitial observational management of hydronephrosis in infants with reduced differential renal function and non-obstructive drainage parameters.
J Pediatr Urol
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Division of Urology, Children's National Medical Center, Washington, DC, USA.
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- Hydronephrosis from UPJ obstruction is common in infants with prenatal diagnosis, leading to surgeries like pyeloplasty due to drainage issues or kidney function decline, but the natural history of cases with non-obstructive drainage and reduced renal function is not well understood.
- The study analyzed data from patients with significant hydronephrosis and low differential renal function, observing them over time to determine how many experienced worsening kidney drainage or function decline.
- Out of 29 patients studied over an average of 2.8 years, nearly half showed worsening drainage, with some requiring surgery, while a few managed to improve without obstructive patterns.