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Rationale: Endometrial vascular dystrophy is a rare and poorly understood pathological condition characterized by tortuous and dilated blood vessels visible under hysteroscopy. Diagnosing this condition is challenging due to its potential resemblance to more severe lesions, such as endometrial hyperplasia or carcinoma. Narrow-band imaging (NBI) technology enhances the visualization of superficial vascular structures, offering a new perspective for diagnosis. This study aims to explore the application value of NBI technology in identifying endometrial vascular abnormalities, thereby improving diagnostic accuracy and differentiating this condition from more serious pathologies.
Patient Concerns: Case 1 is a 32-year-old woman presenting with vaginal bleeding for 8 days and a history of intermittent bleeding for 2 months. Case 2 is a 47-year-old woman with increased menstrual flow and prolonged periods for the past 2 months. Hysteroscopy revealed endometrial vascular dystrophy in both cases, with the presence of endometrial polyps.
Diagnoses: Both patients were diagnosed with endometrial vascular dystrophy and endometrial polyps.
Interventions: Hysteroscopy in both cases revealed a multitude of curved and dilated cord-like capillary loops, along with endometrial polyps. Targeted biopsies and polyp excision were performed.
Outcomes: Both patients received levonorgestrel-releasing intrauterine system treatment and showed symptom improvement at 6-month follow-up. Pathology confirmed endometrial polyps and secretory phase endometrium, with no malignancy.
Lessons: This study emphasizes the importance of NBI technology in identifying and diagnosing endometrial vascular dystrophy and its associated conditions, such as endometrial polyps. NBI provides clearer vascular imaging, aiding in precise targeted biopsies, thereby enhancing diagnostic accuracy and therapeutic efficacy. This research highlights the potential of NBI as a valuable tool in gynecological endoscopy for the diagnosis of rare endometrial conditions.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12237382 | PMC |
http://dx.doi.org/10.1097/MD.0000000000041807 | DOI Listing |
Geburtshilfe Frauenheilkd
September 2025
Institute for Molecular and Cellular Anatomy, University of Regensburg, Regensburg, Germany.
Aim: Endometriosis is a gynecological disorder characterized by endometrial-like tissue outside the uterus. This study evaluates the vascularization and proliferation of human endometriosis and endometrium tissues engrafted onto the chorioallantoic membrane of chicken embryos using immunohistochemistry and laser speckle contrast analysis imaging. For the assessment of clinical relevance, a comparison between laboratory and clinical data was performed.
View Article and Find Full Text PDFArkh Patol
September 2025
G.M. Savelyeva City Clinical Hospital No. 31, Moscow, Russia.
Unlabelled: The question of the degree of influence of uterine artery embolization (UAE) on fertility is open. It is important to evaluate the pathomorphological structure and functional activity of the endometrium, the disruption of which can lead to infertility.
Objective: To study morpho-functional changes in the endometrium of patients with uterine fibroids before and after UAE.
J Reprod Dev
August 2025
Cooperative Department of Veterinary Medicine, School of Veterinary Medicine, Iwate University, Iwate 020-8550, Japan.
Luteal blood flow (LBF) is essential for progesterone (P) biosynthesis in the corpus luteum (CL) and affects bovine fertility. However, the mechanism by which LBF affects fertility remains unclear. This study was conducted to investigate the effects of LBF on endometrial P concentrations and gene expression.
View Article and Find Full Text PDFGeorgian Med News
June 2025
6Municipal State Enterprise "City Center for Human Reproduction" under the Public Health Department, Almaty, Kazakhstan.
Introduction: Antiphospholipid syndrome is an autoimmune disease marked by antiphospholipid antibodies, causing thrombosis and obstetric complications.
Objectives: This study explores molecular mechanisms, endometrial receptivity, and clinical parameters linked to APS, focusing on pregnancy complications such as miscarriage, preterm delivery, recurrent implantation failure (RIF), and thrombosis.
Patients And Methods: A systematic review was conducted through Scopus, WoS, PubMed, Cochrane, and Google Scholar, including studies published between 2019 and 2024.
Folia Med (Plovdiv)
August 2025
Sultan Qaboos University (SQU) and University Hospital of the University Medical City, Muscat, Oman.
An endometrial polyp (EP) is an abnormal growth of the endometrium inside the uterine cavity. Histologically, the polyp contains glandular, stromal, vascular (thick-walled vessels), and connective tissue elements (fibrous stroma). The most common symptoms of patients with endometrial polyps are abnormal bleeding and infertility.
View Article and Find Full Text PDF