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We report a case of a complete cricothyroid membrane soft tissue defect successfully reconstructed with a synthetic, resorbable, hybrid-scale fiber matrix (Restrata). This matrix offers an alternative to traditional allogeneic, xenogeneic, and biologic reconstructive options while potentially avoiding the complications associated with it.
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http://dx.doi.org/10.1002/lary.32402 | DOI Listing |
Laryngoscope
July 2025
Division of Laryngology, Department of Otolaryngology-Head and Neck Surgery, Emory University, Atlanta, Georgia, USA.
We report a case of a complete cricothyroid membrane soft tissue defect successfully reconstructed with a synthetic, resorbable, hybrid-scale fiber matrix (Restrata). This matrix offers an alternative to traditional allogeneic, xenogeneic, and biologic reconstructive options while potentially avoiding the complications associated with it.
View Article and Find Full Text PDFWounds
September 2024
Podiatric Medicine and Surgery, Department of Orthopedics, University of Louisville, Louisville, KY.
Background: Pyoderma gangrenosum (PG) is a rare skin condition that is challenging for both patients and physicians alike. It is extremely painful and can become debilitating for many patients. PG has a mortality rate of 16% at 8 years, and patients with PG have a threefold risk of death compared to the general population.
View Article and Find Full Text PDFCase Rep Oncol
June 2024
Head and Neck Specialists, HCA South Atlantic, HCA Healthcare, Charleston, SC, USA.
Introduction: Patients with head and neck cancer often necessitate complex reconstructions, considering both functional and esthetic concerns. Reconstructions are further complicated by previous radiation therapy and patient co-morbidities, which impair wound healing. A recently introduced synthetic hybrid-scale fiber matrix has been shown to provide durable wound coverage and promote tissue healing as an alternative to traditional biologic allogenic and xenogenic skin substitutes.
View Article and Find Full Text PDFBackground: Wide excision of soft tissue tumors or infections often results in large defects that can be challenging to manage. Advanced treatment modalities-including NPWT, skin grafts, and xenografts-can all be considered for post-resection wound management, but each has its limitations. An SHSFM, engineered to resemble human extracellular matrix, has demonstrated positive wound healing outcomes in prior studies.
View Article and Find Full Text PDFPlast Reconstr Surg Glob Open
February 2024
From the Department of Orthopaedic Surgery, Texas Tech University Health Sciences Center, Lubbock, Tex.
Traditionally, full-thickness wounds with exposed structures are treated with flap coverage or dermal regenerative templates. Most dermal regenerative templates are biologic in origin, but recently synthetic options have become available. One such product is a synthetic hybrid-scale fiber matrix (SHSFM).
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