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Lung transplantation is a critical treatment for patients with end-stage lung disease, demanding precise intraoperative anesthetic management. This study aims to assess the current state of anesthesia management in lung transplant surgeries across China. An online survey was conducted in June 2024 among anesthesiology trainees from Wuxi People's Hospital, covering those trained between 2015 and 2024. The survey, comprising 34 questions, was distributed to participants who were stratified into intermediate and senior groups based on their clinical experience and professional designation. Out of 85 eligible anesthesiologists, 70 (82.4%) from 52 hospitals across 22 provinces in China responded. The most commonly used induction agent was etomidate (95.7%), followed by propofol (58.6%). Sufentanil was universally employed for intraoperative analgesia (100%), alongside remifentanil (71.4%) and oxycodone (24.3%). Extracorporeal membrane oxygenation (ECMO) was the predominant mechanical support used (98.6%), while pressure-controlled ventilation was the preferred mode (95.7%). Significant variations were observed in anesthetic practices, including fluid management, coagulation monitoring, and the use of transesophageal echocardiography (TEE). This study underscores the critical role of anesthesiologists in lung transplantation and highlights the need for standardization and enhanced education to improve patient outcomes. Future research should focus on refining anesthetic protocols and integrating advanced monitoring tools to elevate the safety and efficacy of lung transplants in China.
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http://dx.doi.org/10.1038/s41598-025-10389-0 | DOI Listing |
Eur J Case Rep Intern Med
July 2025
Intensive care unit, Clinical Hospital Sveti Duh, Zagreb, Croatia.
Background: Tacrolimus is a commonly used immunosuppressant with well-defined side effects, including hypertriglyceridemia and hyperglycaemia. However, acute pancreatitis is still not widely recognized as an adverse event related to tacrolimus.
Case Presentation: A 60-year-old male was admitted to the intensive care unit with symptoms and signs of acute pancreatitis.
[This corrects the article DOI: 10.1183/23120541.00623-2024.
View Article and Find Full Text PDFChron Respir Dis
September 2025
Department of Pulmonology, II.Medical Clinic and Polyclinic, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Case presentationDescription of a patient with a progressive destructive lung disease resembling pleuroparenchymal fibroelastosis, liver cirrhosis and bone marrow changes. Genetic workup identified a rare heterozygous coding variant in the (telomerase reverse transcriptase) gene c.472 C>T; p.
View Article and Find Full Text PDFBr J Haematol
September 2025
Department of Internal Medicine, National Taiwan University Cancer Center, Taipei, Taiwan.
Pulmonary chronic graft-versus-host disease (cGVHD), particularly bronchiolitis obliterans syndrome (BOS), is a severe complication of allogeneic haematopoietic stem cell transplantation (allo-HSCT) with significant morbidity and mortality. This report, developed collaboratively by experts from the Taiwan Society of Blood and Marrow Transplantation (TBMT) and the Taiwan Society of Pulmonary and Critical Care Medicine (TSPCCM), provides consensus statements for the diagnosis, surveillance and management of pulmonary cGVHD. Early detection through pulmonary function tests (PFTs) is critical, with serial monitoring recommended after allo-HSCT.
View Article and Find Full Text PDFJ Med Case Rep
September 2025
Department of Anesthesiology, LMU University Hospital Munich LMU, Marchioninistrasse 15, 81377, Munich, Germany.
Background: The treatment of critically ill patients in intensive care units is becoming increasingly complex. For example, organ transplants are regularly carried out, the recipients are seriously ill, and the postoperative course can be complicated. This is why organ replacement and hemadsorption procedures are becoming increasingly important.
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