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Article Abstract
Objective: commonly causes nosocomial infections, and the rise of colistin-resistant strains poses a significant challenge to public health. This research aims to assess the worldwide prevalence of colistin resistance in isolates through a systematic review of scientific literature.
Methods: We conducted a systematic literature review of relevant studies available in the PubMed, Scopus, and Web of Science databases up to December 2023. Following this, a meta-analysis was performed using Stata software to determine the overall prevalence of colistin resistance in isolates and to conduct subgroup analyses.
Results: This meta-analysis reviewed 682 studies and found a global prevalence of colistin resistance at 13% among all isolates. Notably, the data shows an increase in colistin resistance from 6% in 2010 to 18% in 2023.
Conclusion: This study presents evidence of a substantial global prevalence of colistin resistance among clinical isolates of . It is recommended to conduct regular surveillance and testing for colistin resistance to effectively monitor and address this public health issue.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12320877 | PMC |
| http://dx.doi.org/10.1080/17460913.2025.2527534 | DOI Listing |
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