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Purpose: The purpose of this study is to evaluate the gap balance after implantation in patients who have undergone total knee arthroplasty (TKA) via functional alignment (FA) by comparing the virtual gap in preoperative simulation. To facilitate the evaluation of balance characteristics, a control group consisted of patients who underwent anatomical alignment (AA) with the articular surfaces tilted medially and set up in neutral alignment.
Methods: We retrospectively analyzed data from 321 consecutive knees of patients with varus knee osteoarthritis who underwent primary cruciate-retaining TKA from September 2017 to July 2023. The FA group included 140 knees that were operated on via a robotic arm based on kinematic alignment, and the AA group included 93 knees that were operated on via a navigation system. The two groups were stratified according to the timing of surgery that corresponded to changes in the surgeon's surgical technique. After osteotomy, the implant gap was measured via a digital tensioner at 0°, 30°, 60°, 90° and 120° flexion angles with 30 pounds of tension stress applied, and the gaps were compared between the two groups.
Results: The gap between the implants in the medial compartment was stable in FA, with no widening of more than 2 mm, including the mid-flexion position. In AA, the gap tended to open with flexion and was significantly larger than in FA at 60° (FA: 1.1 ± 1.5 mm, AA: 1.8 ± 1.9 mm), 90° (FA: 1.2 ± 1.5 mm, AA: 2.2 ± 2.0 mm) and 120° (FA: 1.4 ± 1.6 mm, AA: 2.8 ± 2.1 mm) ( < 0.05). In the lateral compartment, the gap was significantly larger in AA than in FA at all the angles ( < 0.05).
Conclusion: Compared with AA, FA achieved balance at all knee flexion angles. FA can achieve a well-balanced knee with high reproducibility and may allow the surgeon to consistently obtain better balance.
Level Of Evidence: Level III prospective cohort study.
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http://dx.doi.org/10.1002/jeo2.70315 | DOI Listing |
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University of Hawai'i Cancer Center, Honolulu, Hawaii, USA.
The Oncotype DX test is standardly used for patients with early-stage, hormone-receptor-positive, HER2-negative breast cancers to determine the benefit from chemotherapy and the likelihood of distant recurrence. The relationship between Oncotype DX recurrence scores and race/ethnicity is still being studied. This retrospective study aims to evaluate the relationship between Oncotype DX recurrence scores, race/ethnicity, and clinicopathological factors and to support the applicability of the Oncotype DX test for a diverse breast cancer population of Hawaii.
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Clin Kidney J
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Hypertension is a pervasive and progressive complication in chronic kidney disease (CKD) patients, affecting up to 90% of those in advanced stages or on dialysis. A particularly insidious aspect of this condition is nocturnal hypertension, characterized by high blood pressure (BP) during sleep and a blunted or absent nighttime BP dipping-phenomena associated with accelerated CKD progression and increased cardiovascular risk. Despite its strong prognostic significance, nocturnal hypertension remains underdiagnosed due to limited use of ambulatory BP monitoring.
View Article and Find Full Text PDFFront Public Health
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View Article and Find Full Text PDFAntimicrob Steward Healthc Epidemiol
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