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http://dx.doi.org/10.1016/j.jcmg.2025.05.015DOI Listing

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Takotsubo syndrome: Unraveling the mystery behind its triggers (Review).

Int J Mol Med

November 2025

Department of Acupuncture and Rehabilitation, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan 646000, P.R. China.

Takotsubo syndrome (TTS) is a clinical condition characterized by left ventricular dysfunction, clinically mimicking acute coronary syndrome. Despite significant advancements in understanding TTS, more questions about its underlying pathological mechanisms remain unresolved. The present review offered current data on the underlying pathological mechanisms of TTS, including central nervous system structural and functional alterations, sympathetic nervous system overstimulation, excessive catecholamine secretion, shifts in adrenergic receptors (ARs) distribution and balance, hormone influences, epicardial vasospasm, endothelial dysfunction and genetic predispositions.

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Cardiovascular magnetic resonance characteristics of focal takotsubo syndrome.

Eur J Radiol

October 2025

Department of Diagnostic and Interventional Radiology, University Hospital Bonn, Venusberg-Campus 1, 53127 Bonn, Germany; Quantitative Imaging Laboratory Bonn (QILaB), University Hospital Bonn, Venusberg-Campus 1, 53127 Bonn, Germany. Electronic address:

Aims: Focal takotsubo syndrome (TTS) is rare, and limited data are available on its cardiovascular magnetic resonance (CMR) characteristics. We aimed to define CMR characteristics and disease patterns of focal TTS.

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