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The COVID-19 pandemic has highlighted the need to better understand the dynamics of disease spread in cities in order to develop efficient and effective epidemiological strategies. In this study, we utilise fine-grained spatiotemporal population data obtained from mobile devices to identify areas and time of day that may contribute to COVID-19 spread, and investigate how they change throughout different waves of the pandemic. To evaluate the potential risk to city residents, we analyse the correlation between the effective reproduction number and population dynamics at locations regularly visited by these residents. Our case study of Tokyo identifies highly-correlated areas at a fine-grained level, revealing shifts in these areas within cities and across urban and suburban regions as the pandemic progresses. We also explore the characteristics of the potential areas of concern through the lenses of points of interest and population dynamics. Our findings have implications for comprehensively understanding the spatiotemporal dynamics of COVID-19 and offer insights into public health interventions for managing pandemics.
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http://dx.doi.org/10.1038/s41598-025-06658-7 | DOI Listing |
J Healthc Sci Humanit
January 2024
Program Manager, Center for Biomedical Research/Research Centers in Minority Institutions (TU CBR/RCMI), Department of Biology, College of Arts and Sciences (CAS), Tuskegee University, Phone: (334) 724-4391, Email:
The emergence of the Novel COVID-19 Pandemic has undoubtedly impacted the lives of individuals across the globe. It has drawn the attention of major public health agencies as they work intensely towards understanding the behavior of the virus causing the disease, while simultaneously establishing ways to curb the spread of the virus among populations. As of the time of writing, 7,949,973 confirmed cases have been reported globally; with the United States (US) contributing to 26.
View Article and Find Full Text PDFJ Healthc Sci Humanit
January 2024
Assistant Professor & Clinical Coordinator, Health Informatics Program, School of Health Professions, State University of New York Downstate Health Sciences University, 450 Clarkson Avenue, MSC 94, Brooklyn, NY 11203, (718) 270-7738, Fax: (718) 270-7739 Email:
COVID-19 variants continue to infect thousands of people even though the end of the pandemic was announced on May 11, 2023. Nextstrain CoVariants (CoVariants) genomic databases provide detailed information about more than 31 variants of COVID-19 viruses that have been identified through genomic sequencing, showing the mutations they carry. Mutated viruses may yield a negative result for a gene target using a PCR test that has a positive COVID-19 test result.
View Article and Find Full Text PDFFront Microbiol
August 2025
Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA, United States.
Medical interventions, such as masks, were a cornerstone in mitigating the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Since 2019, the scientific community has increasingly focused on exploring avenues for pandemic prevention and preparedness to enhance responses to future viral outbreaks. One such area of interest explores the use of additives, such as silicon nitride (Si₃N₄), in masks to enhance the antiviral properties of personal protective equipment.
View Article and Find Full Text PDFBMC Public Health
September 2025
Department of Mathematics, Rheinland-Pfälzische Technische Universität Kaiserslautern-Landau, Gottlieb-Daimler-Str.48, Kaiserslautern, 67663, Germany.
We study the dynamics of coexisting influenza and SARS-CoV-2 by adapting a well-established age-specific COVID-19 model to a multi-pathogen framework. Sensitivity analysis and adjustment of the model to real-world data are used to investigate the influence of age-related factors on disease dynamics. Our findings underscore the critical role that transmission rates play in shaping the spread of influenza and COVID-19.
View Article and Find Full Text PDFIntroduction: A 264-d isolation simulation, SFINCSS-99, was conducted in Moscow to replicate typical scenarios on an orbital space station. One long-term group of four Russian crewmembers occupied the isolation complex for most of the duration (240 d), while two international groups of four each spent 110 d successively at the complex. Additionally, there were several short visits by medical personnel.
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