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Neurofibromatosis type 1 (NF-1) leads to cutaneous, neurological, and musculoskeletal manifestations. Congenital pseudarthrosis of the tibia treatment is considered aggressive in achieving bone union. Most of those patients get a short limb at the end of treatment because of pathological bone resection and malalignment. One of the manifestations that can appear in patients is localized hemihypertrophy of the limb. In our case, we present the first time a coexistence of congenital pseudarthrosis of the tibia and hemihypertrophy in the same leg was reported.
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http://dx.doi.org/10.5435/JAAOSGlobal-D-25-00030 | DOI Listing |
Malays Orthop J
July 2025
Department of Orthopaedics and Traumatology, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Introduction: Congenital pseudarthrosis of the tibia (CPT) is challenging to treat. The main issues following surgery are non-union, refracture, limb deformity and length discrepancy. We evaluated the surgical outcome of children operated in our centre.
View Article and Find Full Text PDFJ Plast Reconstr Surg
July 2025
Department of Orthopaedic Surgery, Nara Medical University, Nara, Japan.
A 39-year-old woman diagnosed with persistent congenital tibial pseudoarthrosis until adulthood presented with a right leg angular deformity, associated pain, and significant limb length discrepancy. Over a 17-year period, the case was closely monitored and treated through excision of the pseudarthrosis, vascularised fibular graft with bone marrow-derived and cultured mesenchymal cells, combined with highly purified β-tricalcium phosphates, internal fixation, and the application of a ring Ilizarov fixator. The successful union of bones and correction of deformities was achieved through consideration of both mechanical and biological aspects.
View Article and Find Full Text PDFJ Patient Rep Outcomes
July 2025
Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada.
Background: LIMB-Q Kids is a new patient-reported outcome measure (PROM) for children and adolescents with Lower limb differences (LLDs). This international field test study aimed to evaluate the psychometric properties of LIMB-Q Kids.
Methodology: Patients from pediatric orthopaedic clinics with a diagnosis of LLDs were recruited.
Orphanet J Rare Dis
July 2025
Department of Orthopedics, Hunan Children's Hospital, NO.86 Ziyuan Road, Yuhua District, Changsha City, 410007, Hunan Province, China.
Background: The combined surgery with tibial intramedullary (IM) rod fixation across the ankle for the treatment of Crawford IV congenital pseudarthrosis of the tibia (CPT) is the most classic and effective surgical treatment method. The aim of this study is to explore the long-term clinical efficacy of combined surgery for the treatment of Crawford IV congenital pseudarthrosis of the tibia (CPT).
Methods: A retrospective analysis was conducted on 82 cases of Crawford IV CPT that underwent combined surgical treatment with tibial IM rod fixation through the ankle, to evaluate their long-term clinical efficacy and postoperative complications.
J Neurosurg Pediatr
July 2025
1Department of Neurological Surgery, Doernbecher Children's Hospital, Oregon Health & Science University, Portland; and.
Objective: Occipitocervical fusion (OCF) in children fails at a rate of up to 20% despite multiple technical advances; while the literature reports multiple grading scales of radiographic fusion, none function independently of the surgical technique or type of osseous graft used. In this study, the authors sought to establish 1) a novel reproducible surgical technique with low failure rates and 2) a new, easily applied radiological scoring system to objectively evaluate arthrodesis.
Methods: The authors conducted a single-institution retrospective cohort study of 21 patients who underwent OCF with and without rib autograft fixation from January 2015 to May 2022.