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Objectives: To evaluate the erosive potential of a soft drink modified with film-forming polymers and calcium on bovine enamel and dentin.
Methods: Sprite Zero Sugar was modified with linear sodium polyphosphate (LPP-10 g/L) and sodium trimetaphosphate (TMP-10 g/L), individually or combined with calcium lactate pentahydrate (CLP-4.35 g/L). Enamel and dentin specimens were randomly assigned into six groups (n = 10/substrate): 1. C- (negative control-no modification); 2. LPP; 3. TMP; 4. LPP+CLP; 5. TMP+CLP; 6. C+ (positive control-CLP). The specimens underwent an erosion-remineralization cycling. Surface loss (SL, in μm) was measured with an optical profilometer. Color and viscosity of the drinks were analyzed. Data were statistically analyzed (α=0.05).
Results: For enamel and dentin, LPP significantly reduced the erosive effect of the drink compared to C- (p < 0.001 for both), with reductions of approximately 53 % and 41 %, respectively. TMP showed no significant difference from C- for both substrates. C+ reduced SL by 87 % in enamel and 38 % in dentin when compared to C- (p < 0.001). When CLP was combined with the polymers, in enamel, a 97 % reduction in SL for LPP+CLP and TMP+CLP was observed. In dentin, reductions of 56 % and 48 % were observed for LPP+CLP and TMP+CLP. No significant differences were observed between the groups and the C- regarding color and viscosity (p > 0.05).
Conclusions: All solutions containing calcium lactate (CLP) were effective in reducing the erosive potential of the original soft drink. The combinations of CLP with LPP or TMP significantly enhanced protection, especially for dentin. Notably, LPP alone was effective in minimizing erosion of both enamel and dentin.
Clinical Relevance: Reducing the erosion potential of soft drinks may benefit non-collaborative individuals with high risk for erosive tooth wear.
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http://dx.doi.org/10.1016/j.jdent.2025.105935 | DOI Listing |
JBMR Plus
October 2025
Department of Endocrinology, Austin Health, Melbourne, 3084, Australia.
Medication-related osteonecrosis of the jaw (MRONJ) is a rare but well-recognized complication of treatment with antiresorptive agents. Medication-related osteonecrosis of the external auditory canal (MROEAC), on the other hand, is even rarer and mostly reported during bisphosphonate exposure. Its pathophysiology is thought to involve complex multifactorial processes, including inhibition of bone remodeling, altered angiogenesis, infection, and inflammation.
View Article and Find Full Text PDFFront Plant Sci
August 2025
Country College of Soil and Water Conservation Science and Engineering, Northwest A&F University, Xianyang, Shaanxi, China.
Introduction: The discrepancies in near-soil-surface hydrologic processes triggered by herbage spatial distribution pattern greatly influence the variation in hillslope erosion process. However, knowledge about the influence of herbage spatial distribution pattern on hillslope erosion is still limited.
Methods: In the current study, runoff plots (length × width × depth, 2 × 1 × 0.
ACS Appl Mater Interfaces
September 2025
University of Science and Technology of China, Hefei, Anhui 230027, People's Republic of China.
The development of ultrablack coatings with exceptional absorption (>98%) has historically faced significant scientific and engineering challenges, primarily due to limitations in material selection, structural design, and practical durability. Considering the difficulties in practical applications of ultrablack materials with micro/nano structures and the limitations of planar ultrablack coatings in optical performance, we introduce an innovative integration of conventional planar ultrablack coatings with a specifically engineered trilayer antireflection architecture. This hybrid system incorporates a refractive index distribution (1.
View Article and Find Full Text PDFInt J Infect Dis
September 2025
SAMRC Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa; Department of Microbiology and Biochemistry, Faculty of Natural and Agricultural Sciences, University of the Free State, Bloemfontei
Background: Mycobacterium simiae is a slow-growing environmental nontuberculous mycobacterium (NTM), commonly isolated from soil and water. M. simiae is not known to transmit zoonotically or via human-to-human contact; infection is presumed to occur through direct environmental exposure.
View Article and Find Full Text PDFJ Med Chem
September 2025
Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, No.17, Third Section of Renmin South Road, Chengdu 610041, China.
Rheumatoid arthritis (RA) is a systemic autoimmune disease, and a large number of patients do not respond well to existing treatment strategies. Our previous report has discovered that the cyclic lipopeptide (CLP) daptomycin (DAP) has a good suppressive arthritis activity in mice. In this study, we have designed and synthesized five novel DAP-derived CLPs by structural optimization on the loop of DAP and further studied their anti-RA effects in vitro and in vivo.
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