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Article Abstract
Motivation: Haplotagging is a method for linked-read sequencing, which leverages the cost-effectiveness and throughput of short-read sequencing while retaining part of the long-range haplotype information captured by long-read sequencing. Despite its utility and advantages over similar methods, existing linked-read analytical pipelines are incompatible with haplotagging data.
Results: We describe Harpy, a modular and user-friendly software pipeline for processing all stages of haplotagged linked-read data, from raw sequence data to phased genotypes and structural variant detection.
Availability And Implementation: https://github.com/pdimens/harpy.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12198493 | PMC |
| http://dx.doi.org/10.1093/bioadv/vbaf133 | DOI Listing |
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