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Precision spraying technology has attracted increasing attention in orchard production management. Traditional chemical pesticide application relies on subjective judgment, leading to fluctuations in pesticide usage, low application efficiency, and environmental pollution. This study proposes a machine vision-based precision spraying control system for orchards. First, a canopy leaf wall area calculation method was developed based on a multi-iteration GrabCut image segmentation algorithm, and a spray volume calculation model was established. Next, a fuzzy adaptive control algorithm based on an extended state observer (ESO) was proposed, along with the design of flow and pressure controllers. Finally, the precision spraying system's performance tests were conducted in laboratory and field environments. The indoor experiments consisted of three test sets, each involving six citrus trees, totaling eighteen trees arranged in two staggered rows, with an interrow spacing of 3.4 m and an intra-row spacing of 2.5 m; the nozzle was positioned approximately 1.3 m from the canopy surface. Similarly, the field experiments included three test sets, each selecting eight citrus trees, totaling twenty-four trees, with an average height of approximately 1.5 m and a row spacing of 3 m, representing a typical orchard environment for performance validation. Experimental results demonstrated that the system reduced spray volume by 59.73% compared to continuous spraying, by 30.24% compared to PID control, and by 19.19% compared to traditional fuzzy control; meanwhile, the pesticide utilization efficiency increased by 61.42%, 26.8%, and 19.54%, respectively. The findings of this study provide a novel technical approach to improving agricultural production efficiency, enhancing fruit quality, reducing pesticide use, and promoting environmental protection, demonstrating significant application value.
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http://dx.doi.org/10.3390/s25123799 | DOI Listing |
Zhonghua Jie He He Hu Xi Za Zhi
September 2025
Department of Allergy, Beijing Key Laboratory of Precision Medicine for Diagnosis and Treatment on Allergic Diseases, National Clinical Research Center for Dermatologic and Immunologic Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
Inhaled and intranasal corticosteroids are widely used in the management of allergic respiratory diseases. Delayed drug hypersensitivity reactions to budesonide are a rare adverse drug reaction characterized by non-immunoglobulin E (IgE)-mediated clinical manifestations, including localized or systemic contact dermatitis, mucosal edema, and paradoxical worsening of pre-existing symptoms. However, such reactions are often underdiagnosed due to atypical presentations.
View Article and Find Full Text PDFCNS Drugs
September 2025
Global Health Neurology Lab, Sydney, NSW, 2150, Australia.
Acute ischemic stroke (AIS) remains a leading cause of mortality and long-term disability globally, with survivors at high risk of recurrent stroke, cardiovascular events, and post-stroke dementia. Statins, while widely used for their lipid-lowering effects, also possess pleiotropic properties, including anti-inflammatory, endothelial-stabilizing, and neuroprotective actions, which may offer added benefit in AIS management. This article synthesizes emerging evidence on statins' dual mechanisms of action and evaluates their role in reducing recurrence, improving survival, and mitigating cognitive decline.
View Article and Find Full Text PDFJ Drug Target
September 2025
Department of Pharmaceutics, ShriRam College of Pharmacy, Banmore, Morena-476444, Madhya Pradesh, India.
Tuberculosis (TB) continues to cause significant global mortality, highlighting the need for improved drug delivery systems. The objective of this paper focuses in describing the formulation, optimization and in vivo assessment of rifampicin encapsulated PLGA microparticles for site-specific inhalation therapy. Microparticles for inhalation were produced by spray drying, and the DoE methodology was applied to reach the most suitable aerodynamic properties (mass median aerodynamics diameter (MMAD) 2.
View Article and Find Full Text PDFInt J Nanomedicine
September 2025
Department of Plastic Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, People's Republic of China.
Diabetic wounds are characterized by complex pathologies, such as vascular changes, nerve damage, and immune dysfunction, which make healing difficult. Hydrogel microspheres have shown great potential in the field of wound treatment due to their excellent biocompatibility, high water content, and soft physical properties. The review summarizes the preparation methods of hydrogel microspheres in detail, including microfluidic technology, spray method, electro spraying, emulsion method, phase separation, photomask method, and 3D printing technology.
View Article and Find Full Text PDFCureus
August 2025
Anaesthesia and Surgical Intensive Care, Changi General Hospital, Singapore Health Services, Simei, SGP.
Effective airway topicalization is essential for awake tracheal fiberoptic intubation (ATI) in patients with a difficult airway. Traditional methods often result in inadequate anesthesia at the laryngeal inlet, leading to patient discomfort, procedural difficulty, and excessive local anesthetic (LA) use. This case series introduces a novel, resource-efficient topicalization technique using standard operating theatre equipment.
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