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Micro- and nanosensors are pivotal tools in various fields, revolutionizing the way in which we monitor and interact with biological, environmental, and industrial processes [...].
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http://dx.doi.org/10.3390/mi16060614 | DOI Listing |
Biosens Bioelectron
December 2025
Integrative Biomedical Materials and Nanomedicine Laboratory, Medicine and Life Sciences Department, Universitat Pompeu Fabra, Carrer Del Doctor Aiguader 88, 08003, Barcelona, Spain. Electronic address:
Labile Zn is emerging as a quantitative driver, not just a biomarker, of metastasis, yet rapid, second-resolved intracellular measurement remains elusive. Here we engineer terpyridine-functionalised, hollow Au@SiO nanocapsules (NCs@TPY) and couple their SERS signal to cell-specific partial-least-squares (PLS) chemometrics, yielding an 8-log dynamic range (10 - 10 M), a low-nanomolar detection limit and ≤4.5 % cross-validated error while rejecting Ca/Mg interference.
View Article and Find Full Text PDFBiomed Mater
August 2025
Department of Engineering and System Science, National Tsing Hua University, Hsinchu, Taiwan, Republic of China.
Tumor acidosis is a consequence of altered metabolism that primarily takes place due to lactate secretion from anaerobic glycolysis. As a result, many regions within the tumors are chronically hypoxic and acidic. To measure the intratumor pH dynamically, we have fabricated a biocompatible pH nanoparticle sensor using surface-enhanced Raman spectroscopy (SERS-pNPS) and monitored continuous pH levels in three-dimensional multicellular spheroids.
View Article and Find Full Text PDFACS Sens
July 2025
College of Mechatronics and Control Engineering, Shenzhen University, Shenzhen, Guangdong 518060, China.
In this work, we present a novel wearable respiratory monitoring device based on a heterogeneously integrated highly thermosensitive and fast-response nanosensor with a flexible substrate. The sensor is designed based on the ultralow thermal capacitance concept, and the fabricated sensor has a dynamic temperature resolution of 0.016 °C and a time response of 20 μs in laser pulse heating tests and a response time of 10.
View Article and Find Full Text PDFMicromachines (Basel)
May 2025
Faculty of Materials Science and Ceramics, AGH University of Krakow, al. Mickiewicza 30, 30-059 Cracow, Poland.
Micro- and nanosensors are pivotal tools in various fields, revolutionizing the way in which we monitor and interact with biological, environmental, and industrial processes [...
View Article and Find Full Text PDFJ Biomater Appl
June 2025
Hybrid and Composite Technology Laboratory, Research and Development Institute, Vale do Paraíba University, São José dos Campos, Brazil.
Zinc oxide (ZnO) has wide application in engineering, but its use in medical sciences has aroused growing interest. In this context, ZnO nanoparticles were investigated as vehicles for the delivery of methylene blue (MB), a photosensitizer (PS) used in photodynamic therapy (PDT) against . ZnO-NPs were produced by a coprecipitation method and characterized by several techniques, including scanning electron microscopy (SEM), UV-VIS spectroscopy, Fourier transform infrared spectroscopy (FTIR), and X-ray diffraction (XRD).
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