98%
921
2 minutes
20
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12203682 | PMC |
http://dx.doi.org/10.1080/07853890.2025.2525392 | DOI Listing |
Horm Metab Res
September 2025
Clinical Biochemistry, The Royal Wolverhampton NHS Trust, Black Country Pathology Services, Wolverhampton, United Kingdom of Great Britain and Northern Ireland.
Parathyroid hormone (PTH) assays are not standardized and therefore PTH results are interpreted using manufacturer-provided assay-specific reference intervals. Assay-specific PTH reference intervals, however, do not account for between-assay differences and lead to discordance in the diagnosis of normocalcaemic primary hyperparathyroidism (NCPHPT). PTH increases with age independent of vitamin D, renal function, phosphate and ionized calcium.
View Article and Find Full Text PDFTher Adv Endocrinol Metab
September 2025
Endocrinology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, 530 E 74th Street, New York, NY 10021, USA.
Cancer negatively impacts bone health through various mechanisms, including treatment-induced bone loss and malignant bone lesions, often leading to increased fracture risk and higher morbidity and mortality. Antiresorptive agents (bisphosphonates and denosumab) are the current standard of care to reduce the risk of skeletal-related events and prevent treatment-related fragility fractures in patients with cancer. While there is strong evidence to support their benefits in cancer, there is potential room for further reduction in the risk of pathologic and fragility fractures.
View Article and Find Full Text PDFJAMA Surg
September 2025
Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan.
Importance: The transoral endoscopic thyroidectomy vestibular approach (TOETVA) is a scarless surgical technique gaining popularity; however, its safety, cost, and impact on pathological evaluation compared with minimally invasive nonendoscopic thyroidectomy (MINET) remain under evaluation.
Objective: To compare surgical outcomes, pathological considerations, and cost profiles following TOETVA vs MINET using a propensity-matched cohort.
Design, Setting, And Participants: This cohort study included 720 patients undergoing oncoplastic thyroidectomy between January 2021 and January 2023, with 12-month follow-up, at a tertiary referral center in Taipei, Taiwan.
BMC Nephrol
September 2025
Nanping First Hospital Affiliated to Fujian Medical University, Nanping, Fujian, China.
Background: Elevated serum phosphate levels are strongly associated with an increased risk of all-cause mortality in patients with chronic kidney disease (CKD). The aim of this study was to identify independent risk factors for hyperphosphatemia in patients with non-dialysis CKD and use the findings to develop and validate a predictive model for assessing hyperphosphatemia risk.
Methods: Data of patients with CKD discharged from the Department of Nephrology between January 2021 and December 2023 were retrospectively analyzed.
Anim Nutr
September 2025
Institute of Anatomy, Rostock University Medical Center, Gertrudenstraße 9, 18057, Rostock, Germany.
Parathyroid glands (PTG) are essential in maintaining mineral homeostasis, particularly in regulating blood calcium (Ca) and phosphorus (P) levels. The endocrine regulation via parathyroid hormone (PTH) is a prerequisite for the efficient utilization of dietary P. The PTG contain lobules of PTH-producing chief cells surrounded by extracellular collagen.
View Article and Find Full Text PDF