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: Postoperative wound dehiscence is a major complication following spinal metastasis surgery, particularly in patients who receive preoperative radiotherapy or molecular-targeted therapy; however, preventive strategies remain limited. : In this study, we aimed to identify the risk factors for postoperative wound dehiscence and evaluate the clinical utility of a novel curved skin incision (CSI) technique, designed to avoid irradiated areas, in comparison with the conventional midline incision (MI) technique. : Logistic regression analysis was conducted on 107 patients who underwent MI between 2013 and 2018. Based on the results, we developed the CSI technique. Propensity score matching was performed to compare postoperative wound dehiscence in 29 matched pairs of patients treated with either CSI or MI from 2019 to 2021. : Preoperative radiotherapy and molecular-targeted therapy were found to be significant risk factors for wound dehiscence. CSI, which circumvents irradiated skin, was associated with a substantially lower rate of wound dehiscence than MI. : The CSI technique offers a simple, reproducible, and effective surgical approach to reduce postoperative wound complications in high-risk patients. Its clinical benefit, especially for those with prior radiotherapy, suggests that it may serve as a valuable addition to standard spinal metastasis surgery.
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http://dx.doi.org/10.3390/cancers17121973 | DOI Listing |
Injury
September 2025
Washington University School of Medicine, Department of Orthopaedic Surgery, St. Louis, MO, USA. Electronic address:
Introduction: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are increasingly prescribed for Type 2 diabetes and obesity due to their cardiometabolic benefits. However, their effects on fracture healing remain controversial. This study investigates perioperative GLP-1 RA use and outcomes following surgical treatment of lower extremity (LE) fractures.
View Article and Find Full Text PDFInt Ophthalmol
September 2025
Department of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa, 200 Hawkins Dr, 11290A PFP, Iowa City, IA, 52242, USA.
Purpose: To study clinical characteristics and outcomes of penetrating keratoplasty (PK) and deep anterior lamellar keratoplasty (DALK) wound dehiscence.
Methods: This retrospective case series assessed PK and DALK recipients with wound dehiscence at a single institution. We evaluated relationships between dehiscence etiologies, transplant indications, ocular/systemic comorbidities, keratoplasty type, and adverse post-dehiscence outcomes, especially graft failure and visual loss.
Cureus
August 2025
Surgery, Rocky Vista University College of Osteopathic Medicine, Ivins, USA.
Implant extrusion is a rare but serious complication typically linked to infection, poor wound healing, or material intolerance. This case report describes a 79-year-old female patient who experienced extrusion of both a hip prosthesis and an Inspire hypoglossal nerve stimulator (Inspire Medical Systems, Inc., Minnesota, USA), each event associated with the use of Ethibond (Ethicon, Johnson & Johnson, Georgia, USA) sutures.
View Article and Find Full Text PDFInt J Surg Case Rep
September 2025
Department of Otolaryngology, University Hospital Galway, Ireland; Discipline of Otorhinolaryngology, University of Galway, Ireland.
Introduction And Importance: While blunt trauma to the head is a well-recognized cause of middle ear injuries, penetrating traumas are far less common. Due to the close anatomical relations, the potential consequences of such injuries can be catastrophic.
Case Presentation: A man presented following a penetrating injury to the external auditory canal.
PLoS One
September 2025
Maternal-Fetal Medicine, Genetics, and Reproduction Unit. Virgen del Rocío University Hospital, Seville, Spain.
Introduction: Cesarean sections are among the most common obstetric surgeries worldwide. While generally safe, they can be complicated by numerous factors increasing risks for both mother and fetus, and posing significant challenges in clinical practice. In Spain, the absence of unified protocols for managing high-risk cases underscores the need for systematic guidance to improve maternal outcomes and reduce morbidity.
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