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Chemotaxonomic profiling based on secondary metabolites offers a reliable approach for identifying and authenticating medicinal plants, addressing limitations associated with traditional morphological and genetic methods. Recent advances in microfluidics and nanoengineered technologies-including lab-on-a-chip systems as well as nano-enabled optical and electrochemical sensors-enable the rapid, accurate, and portable detection of key metabolites, such as alkaloids, flavonoids, terpenoids, and phenolics. Integrating artificial intelligence and machine learning techniques further enhances the analytical capabilities of these technologies, enabling automated, precise plant identification in field-based applications. Therefore, this review aims to highlight the potential applications of micro- and nanoengineered devices in herbal medicine markets, medicinal plant authentication, and biodiversity conservation. We discuss strategies to address current challenges, such as biocompatibility and material toxicity, technical limitations in device miniaturization, and regulatory and standardization requirements. Furthermore, we outline future trends and innovations necessary to fully realize the transformative potential of these technologies in real-world chemotaxonomic applications.
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http://dx.doi.org/10.3390/nano15120899 | DOI Listing |
Adv Healthc Mater
September 2025
Department of Chemical and Biochemical Engineering, School of Biomedical Engineering, Department of Chemistry, The Centre for Advanced Materials and Biomaterials Research, The University of Western Ontario, London, ON, N6A 5B9, Canada.
Severe bone defects resulting from traumatic injuries or infections are severe skeletal deficiencies that are unable to regenerate on their own. Despite their effectiveness, current treatments including allografts and artificial bone substitutes, have several drawbacks. This includes poor osseointegration, low biocompatibility and biodegradability, limited cell infiltration, and adverse side effects arising from drug-loaded substitutes.
View Article and Find Full Text PDFACS Photonics
August 2025
Department of Physics, University of Washington, Seattle, Washington 98195, United States.
Triggered by advances in atomic-layer exfoliation and growth techniques, along with the identification of a wide range of extraordinary physical properties in self-standing films consisting of one or a few atomic layers, two-dimensional (2D) materials such as graphene, transition metal dichalcogenides (TMDs), and other van der Waals (vdW) crystals now constitute a broad research field expanding in multiple directions through the combination of layer stacking and twisting, nanofabrication, surface-science methods, and integration into nanostructured environments. Photonics encompasses a multidisciplinary subset of those directions, where 2D materials contribute remarkable nonlinearities, long-lived and ultraconfined polaritons, strong excitons, topological and chiral effects, susceptibility to external stimuli, accessibility, robustness, and a completely new range of photonic materials based on layer stacking, gating, and the formation of moiré patterns. These properties are being leveraged to develop applications in electro-optical modulation, light emission and detection, imaging and metasurfaces, integrated optics, sensing, and quantum physics across a broad spectral range extending from the far-infrared to the ultraviolet, as well as enabling hybridization with spin and momentum textures of electronic band structures and magnetic degrees of freedom.
View Article and Find Full Text PDFSmall
July 2025
Photovoltaic Lab - Micro and Nano Technologies Group (MNT), Electronic Engineering Department, Universitat Politècnica de Catalunya (UPC), EEBE, Av Eduard Maristany 10-14, Barcelona, 08019, Spain.
(Sb,Bi)(S,Se)(Br,I) pnictogen chalcohalides constitute an emerging family of Van der Waals (VdW) semiconductors with remarkable potential for energy-related applications, including photovoltaics (PV), photocatalysis (PC), and photoelectrocatalysis (PEC). These ternary compounds exhibit a quasi-1D orthorhombic crystalline phase, and an electronic structure analogous to lead-halide perovskites, making them promising candidates for sustainable and high-performance energy devices. This study introduces a new versatile and adaptable synthesis methodology, which combines co-evaporation of binary chalcogenides with reactive annealing under high-pressure halide atmospheres, to fabricate the eight (Sb,Bi)(S,Se)(Br,I) chalcohalides.
View Article and Find Full Text PDFACS Energy Lett
July 2025
Pritzker School of Molecular Engineering, University of Chicago, Chicago, Illinois 60637, United States.
Characterizing the microstructure of all-solid-state batteries (ASSBs) during fabrication and operation is vital for their advancement, particularly as scaling to pouch cell levels introduces challenges in probing large-scale microstructural evolution. This work highlights the potential of synchrotron X-ray micro-computed tomography (sXCT) as a nondestructive, rapid (<30 min), and high-resolution technique for visualizing and quantifying key microstructural features, including overhang, porosity, contact loss, active surface area, and tortuosity, in all-solid-state pouch cells. The large field of view (up to millimeters) of sXCT enables detailed analysis at an industry-relevant scale, bridging the gap between laboratory research and commercial applications.
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August 2025
Laboratory of Bio-physio Sensors and Nanobioengineering, School of Biochemical Engineering, Indian Institute of Technology (BHU) Varanasi, Varanasi, Uttar Pradesh, 221005, India.
A magnetic molecularly imprinted polymer (MMIP) is synthesized for the development of a highly selective and sensitive electrochemical sensing platform targeting enrofloxacin (ENF). The micro-sized mesoporous core-shell MMIP structure is constructed with a magnetite core and an outer shell functionalized using 3-aminopropyltriethoxysilane (APTES) as the monomer. The synthesis is optimized and validated using a range of physical and electrochemical techniques.
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