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Background: The literature reports few instances of spontaneous bowel eviscerations through umbilical hernia sites. Spontaneous rupture of the hernia sac is a less common complication, primarily associated with persistent ascites or congenital wall defects.
Materials And Methods: A systematic review was conducted using the PubMed database-the United States National Library of Medicine, with the search terms "spontaneous bowel evisceration" and "umbilical hernia evisceration". However, several results were deemed unsuitable for this manuscript. From a total of 185 cases, this review was narrowed down to 9 usable reports. Non-English language cases, duplicates, and cases unrelated to the pathology, including pediatrics, malformations, herniation through other organs, and animal cases, were excluded.
Conclusions: Spontaneous evisceration in a hernia is an uncommon yet serious condition. A major risk factor appears to be underlying liver disease with its complications, such as ascites, chronic malnutrition with hypoalbuminemia, and collateral circulation formation. These factors contribute to the susceptibility of the sac and the hernia wall to rupture. However, the limited number of reported cases precludes the establishment of a preferred treatment approach. In the acute phase, the use of prosthetics may be less advisable, but in an elective setting, the cirrhotic patient could be offered repair.
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http://dx.doi.org/10.3390/clinpract15060099 | DOI Listing |
Clin Transl Gastroenterol
September 2025
Lynda K and David M Underwood Center for Digestive Health, Houston Methodist, Houston, TX, USA.
Introduction: Pharmacological therapies for chronic idiopathic constipation (CIC) are useful, but many patients report dissatisfaction from a lack of efficacy and occurrence of adverse events. The vibrating capsule (VC) is an FDA approved non-pharmacologic, treatment for CIC. However, its long-term usefulness in a community setting is unknown.
View Article and Find Full Text PDFInt J Surg Case Rep
August 2025
Nobel Medical College and Teaching Hospital, Biratnagar, Nepal.
Introduction: Transanal evisceration of small bowel through a rectal perforation is a rare surgical presentation, often associated with rectal prolapse. Its occurrence with uterine prolapse is an uncommon finding.
Case Presentation: We report a case of a 50-year-old female with untreated third-degree uterine prolapse and COPD, who presented with transanal evisceration of approximately 100 cm of small bowel following coughing episodes.
Front Cell Infect Microbiol
September 2025
Hunan Key Laboratory of Traditional Chinese Medicine Prescription and Syndromes Translational Medicine, Hunan University of Chinese Medicine, Changsha, China.
Introduction: Sishen Pill (SSP), a classic TCM formula, warms the kidney and spleen, astringes the intestine, and stops diarrhea. Emerging evidence suggests that diarrhea with KYDS is linked to gut microbiota imbalance and altered intestinal enzyme activities. At the same time, SSP has been shown to regulate gut microbiota, improve metabolism, and alleviate intestinal disorders.
View Article and Find Full Text PDFJ Clin Invest
September 2025
Department of Medicine.
A20, encoded by the TNFAIP3 gene, is a protein linked to Crohn's disease and celiac disease in humans. We now find that mice expressing point mutations in A20's M1-ubiquitin-binding zinc finger 7 (ZF7) motif spontaneously develop proximal enteritis that requires both luminal microbes and T cells. Cellular and transcriptomic profiling reveals expansion of Th17 cells and exuberant expression of IL-17A and IL-22 in intestinal lamina propria of A20ZF7 mice.
View Article and Find Full Text PDFAm J Case Rep
September 2025
Department of General Surgery, Second Affiliateda Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
BACKGROUND Phytobezoar-induced small bowel obstruction presents significant management challenges, particularly in patients who either decline surgery or have contraindications. These concretions, predominantly composed of persimmon tannins, account for 0.4-4.
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