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The von Neumann bottleneck and growing energy demands of conventional computing systems require innovative architectural solutions. Although neuromorphic computing is a promising alternative, implementing efficient on-chip learning mechanisms remains a fundamental challenge. Herein, a novel artificial neural platform is presented that integrates three synergistic components: modulation-optimized presynaptic transistors, threshold switching memristor-based neurons, and adaptive feedback synapses. The platform demonstrates real-time synaptic weight modification through correlation-based learning, effectively implementing Hebbian principles in hardware without requiring extensive peripheral circuitry. Stable device operation and successful implementation of local learning rules are confirmed by systematically characterizing a 6 × 6 array configuration. The experimental results demonstrate a correlation between input-output signals and subsequent weight modifications, establishing a viable pathway toward hardware implementation of Hebbian learning in neuromorphic systems.
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http://dx.doi.org/10.1002/adma.202506920 | DOI Listing |
PLoS One
September 2025
Artificial Intelligence Research and Innovation Lab - AIRIL, Dhaka, Bangladesh.
Due to limited literacy among root-level farmers, hydroponic farming in Bangladesh faces significant challenges. Therefore, there is a demand for easy-to-use technical systems to help farmers to monitor and operate smart systems. To address the issue, this study introduces a robust hydroponic system that provides automatic guidelines, monitoring, and a disease detection system.
View Article and Find Full Text PDFJ Invest Dermatol
September 2025
Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA; Sibel Health, Chicago, Illinois, USA; Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, Illinois, USA. Electronic address:
The integration of wearable medical devices and digital health technologies (DHTs) in health care has grown significantly during the past 2 decades, particularly in dermatology, in which objective measurement of symptoms such as itch remains challenging. This review examines the evolution of DHTs in dermatology, focusing on the validation frameworks necessary for their implementation in clinical trials and research. We discuss the key stages of validation: hardware validation to ensure device reliability, analytical validation to transform raw sensor data into meaningful metrics, and clinical validation to demonstrate utility in specific patient populations.
View Article and Find Full Text PDFInt J Comput Assist Radiol Surg
September 2025
Department of Rhythmology, University Heart Center Lübeck, University Hospital Schleswig-Holstein, Ratzeburger Allee 160, Lübeck, 23652, Germany.
Purpose: Ultrasound (US) is commonly used to assess left ventricular motion for examination of heart function. In stereotactic arrhythmia radioablation (STAR) therapy, managing cardiorespiratory motion during radiation delivery requires representation of motion information in computed tomography (CT) coordinates. Similar to conventional US-guided navigation during surgical procedures, 3D US can provide real-time motion data of the radiation target that could be transferred to CT coordinates and then be accounted for by the radiation system.
View Article and Find Full Text PDFNat Commun
September 2025
Computational Science and Technology, KTH Royal Institute of Technology, Stockholm, Sweden.
Biological nervous systems constitute important sources of inspiration towards computers that are faster, cheaper, and more energy efficient. Neuromorphic disciplines view the brain as a coevolved system, simultaneously optimizing the hardware and the algorithms running on it. There are clear efficiency gains when bringing the computations into a physical substrate, but we presently lack theories to guide efficient implementations.
View Article and Find Full Text PDFAm J Clin Pathol
September 2025
Department of Pathology, The Ohio State University College of Medicine, Columbus, OH, United States.
Objective: To determine trends in system and scanner downtime in our institution's digital pathology pipeline since its implementation.
Methods: Scanner and system downtime data were tabulated from a period beginning in 2017 and ending in 2022. Downtime events were categorized based on their etiology, such as image management system related for the overall system or hardware vs software related for the scanner.