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Article Abstract
Background: Venous thromboembolism (VTE) is a multifactorial disease that is associated with long-term morbidity, dysfunction, and mortality. Although numerous studies reported on the prevalence and risk factors of VTE in hospitalized patients, the results varied due to the complexity of the disease and differences in genetic characteristics, social environment, and disease spectrum. Therefore, this study aimed to investigate the prevalence, clinical features, and risk factors for VTE in hospitalized patients in the eastern Liaoning.
Methods: A cross-sectional study was conducted at Liaoning Province Benxi Central Hospital to select patients hospitalized between January and December 2021. All patients underwent a Doppler ultrasound, and medical data, including demographic factors, risk factors, and clinical characteristics, were collected from the Benxi Clinical Biobank. Chi-square tests and logistic regression analysis were employed to identify independent risk or related factors.
Results: A total of 1200 inpatients were eligible for inclusion in the study. The prevalence of VTE was 21.4%. In the multifactorial analysis, five variables were independent risk factors for VTE: age (odds ratio (OR) 1.035; 95% confidence interval (CI) 1.022-1.047), History of confirmed VTE (OR 6.666; 95% CI 3.602-12.338), previous surgical intervention (OR 1.771; 95% CI 1.099-2.854), central venous catheterization (OR 1.852; 95% CI 1.126-3.044), and recent acute infection (OR 1.521; 95% CI 1.101-2.102). Limb pitting edema was an independent clinical correlate of VTE, either unilateral (OR 5.528; 95% CI 3.638-8.402) or bilateral (OR 1.679; 95% CI 1.069-2.637). Of the 238 patients with deep vein thrombosis (DVT) in the lower limbs (with or without pulmonary embolism), distal DVT was more common than proximal DVT (64.3% vs. 20.6%).
Conclusion: The prevalence of VTE in hospitalized patients in eastern Liaoning was high, with certain population-specific risk factors and the vascular location of VTE. It is worthwhile to expand the study of the sample.
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| http://dx.doi.org/10.1016/j.avsg.2025.06.003 | DOI Listing |
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